Almutairi Masaad Saeed, Alnezary Faris S, Alsuwaylim Rasil O, Alsulaymi Ibrahim, Almohammed Omar A, Thabit Abrar K
Department of Pharmacy Practice, College of Pharmacy, Qassim University, Qassim, Saudi Arabia.
Department of Pharmacy Practice, College of Pharmacy, Taibah University, Madinah, Saudi Arabia.
Infect Drug Resist. 2024 Feb 14;17:583-594. doi: 10.2147/IDR.S450281. eCollection 2024.
Diagnosis of infection (CDI) depends on clinical presentation and laboratory testing. Stool diagnostic tests are essential for effective detection of toxigenic strains. No study to date has evaluated the readability of microbiology labs in Saudi Arabia to test for CDI and evaluated the knowledge and practice of healthcare providers regarding CDI management. Therefore, this study aimed to assess the knowledge and practice of healthcare providers in Saudi Arabia regarding CDI diagnosis and treatment.
A cross-sectional, descriptive, questionnaire-based study was conducted on healthcare providers in Saudi Arabia, primarily physicians and clinical pharmacists. The questionnaire was developed based on a literature review and input from infectious diseases experts. The questionnaire was administered online. Data were analyzed using descriptive and inferential statistics.
Of 183 respondents, 27.9% had adequate knowledge on CDI diagnosis and management. The majority were internal medicine specialists (37.7%) working in governmental or semi-governmental hospitals (80.9%) in central (46.6%) or southern (30.1%) regions of Saudi Arabia. Most participants assessed laxative use (86.3%) and reported positive specimens to infection control (67.2%). However, knowledge varied, with 57.4% supporting unnecessary retesting and 53% assuming positive PCR test indicates moderate CDI probability. Factors such as specialization, hospital accreditation status, and bed capacity influenced knowledge levels (p<0.01 for all factors).
The study revealed a significant knowledge gap among Saudi healthcare providers regarding CDI diagnosis, management, and severity classification, highlighting the need for improved education and adherence to guidelines to improve patient outcomes and reduce recurrence risks.
艰难梭菌感染(CDI)的诊断依赖于临床表现和实验室检测。粪便诊断检测对于有效检测产毒菌株至关重要。迄今为止,尚无研究评估沙特阿拉伯微生物实验室对CDI检测的可读性,也未评估医疗服务提供者在CDI管理方面的知识和实践。因此,本研究旨在评估沙特阿拉伯医疗服务提供者在CDI诊断和治疗方面的知识和实践。
对沙特阿拉伯的医疗服务提供者,主要是医生和临床药剂师,进行了一项基于问卷调查的横断面描述性研究。该问卷是根据文献综述和传染病专家的意见制定的。问卷通过在线方式发放。使用描述性和推断性统计方法对数据进行分析。
在183名受访者中,27.9%对CDI诊断和管理有足够的知识。大多数是内科专家(37.7%),在沙特阿拉伯中部(46.6%)或南部(30.1%)地区的政府或半政府医院工作(80.9%)。大多数参与者评估了泻药的使用情况(86.3%),并向感染控制部门报告了阳性标本(67.2%)。然而,知识水平存在差异,57.4%的人支持不必要的重新检测,53%的人认为PCR检测呈阳性表明CDI可能性为中度。专业、医院认证状态和床位容量等因素影响了知识水平(所有因素的p<0.01)。
该研究揭示了沙特医疗服务提供者在CDI诊断、管理和严重程度分类方面存在重大知识差距,突出了需要加强教育并遵守指南以改善患者预后并降低复发风险。