Department of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Department of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Head Neck. 2024 May;46(5):E57-E60. doi: 10.1002/hed.27691. Epub 2024 Feb 20.
A case of retropharyngeal abscess complicated by both artery and nerve injury has rarely been reported.
A 36-year-old woman suddenly presented with right eye visual loss, dilated pupil, reduced direct light reflex, ptosis and ocular motility disorder on the side of inflammation progression, and was diagnosed with retropharyngeal abscess due to Fusobacterium necrophorum. The patient was treated only with antibiotics and, no further surgery was necessary but tracheotomy. Four months later, MRA showed right ICA occlusion and left ICA stenosis. MRI revealed continuous spread of inflammation due to the abscess from the retropharyngeal to the intracranial space.
These severe complications would be attributed to an endothelial damage to the arterial wall and an ischemic neuropathy caused by inflammation and thrombogenesis due to Fusobacterium necrophorum.
This case should provide a better understanding of the mechanism of vascular and cranial nerve injury due to retropharyngeal infections, and highlights the need for early antibiotic therapy and repeated vascular evaluation.
咽后脓肿并发动脉和神经损伤的病例很少见。
一名 36 岁女性突然出现右眼视力丧失、瞳孔扩大、直接光反射减弱、上睑下垂和炎症进展侧眼球运动障碍,被诊断为坏死梭杆菌引起的咽后脓肿。患者仅接受抗生素治疗,无需进一步手术,但需行气管切开术。4 个月后,MRA 显示右侧颈内动脉闭塞,左侧颈内动脉狭窄。MRI 显示由于脓肿从咽后向颅内空间的连续扩散,炎症持续发展。
这些严重并发症归因于动脉壁内皮损伤以及坏死梭杆菌引起的炎症和血栓形成导致的缺血性神经病。
该病例应更好地了解咽后感染引起的血管和颅神经损伤的机制,并强调早期抗生素治疗和反复血管评估的必要性。