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用红毛丹提取物负载的海藻酸钠珠:体外胃肠道消化过程中的特性和稳定性。

Alginate beads loaded with rambutan extract: characterization and stability during in vitro gastrointestinal digestion.

机构信息

Department of Food Science and Technology, Faculty of Agro-Industry, Kasetsart University, Bangkok, Thailand.

出版信息

J Sci Food Agric. 2024 Aug 15;104(10):5712-5723. doi: 10.1002/jsfa.13397. Epub 2024 Feb 29.

DOI:10.1002/jsfa.13397
PMID:38375784
Abstract

BACKGROUND

Fallen young rambutan fruit is an underrated agricultural waste which may contain several bioactive compounds. In this study, fallen young rambutan fruit was assessed regarding its phenolic contents and antioxidant activities. In order to expand its utilization, rambutan extract-loaded hydrogel beads were developed by a basic spherification technique using sodium alginate. The effect of ratios of polymer and extract and different calcium sources were evaluated. The recovery of bioactive compounds from the hydrogel beads was determined using in vitro gastrointestinal digestion models.

RESULTS

Use of 50% (v/v) ethanol yielded rambutan extract with good chemical properties. The production of hydrogel beads using a ratio of 1:3 with calcium lactate provided the highest production yield of 122.94%. The hydrogel beads developed using the ratio of 1:3 with a combination of calcium lactate and calcium chloride showed high recovery of phenolic compounds and antioxidant activity after simulated intestinal digestion, which were greater compared to unencapsulated extract.

CONCLUSION

The findings demonstrate that the ratio of wall material to rambutan extract and the calcium source influence the physical properties, chemical properties and in vitro gastrointestinal digestion stability of alginate beads. The obtained hydrogel beads may have potential for application in the food or pharmaceutical industries. © 2024 Society of Chemical Industry.

摘要

背景

落果的荔枝是一种被低估的农业废弃物,可能含有多种生物活性化合物。在本研究中,评估了落果荔枝的酚类含量和抗氧化活性。为了扩大其利用范围,采用基本的球化技术,用海藻酸钠开发了负载荔枝提取物的水凝胶珠。评估了聚合物和提取物的比例以及不同钙源的影响。使用体外胃肠道消化模型确定了水凝胶珠中生物活性化合物的回收情况。

结果

使用 50%(v/v)乙醇获得了具有良好化学性质的荔枝提取物。使用乳酸钙的比例为 1:3 生产水凝胶珠,产率最高,为 122.94%。使用乳酸钙和氯化钙组合的比例为 1:3 制备的水凝胶珠在模拟肠道消化后显示出较高的酚类化合物和抗氧化活性回收率,与未封装的提取物相比更高。

结论

研究结果表明,壁材与荔枝提取物的比例以及钙源影响海藻酸钠珠的物理性质、化学性质和体外胃肠道消化稳定性。所得水凝胶珠在食品或制药工业中可能具有应用潜力。© 2024 化学工业协会。

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