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[吉尔伯特综合征中的异烟肼乙酰化]

[Isoniazid acetylation in Gilbert's syndrome].

作者信息

Pereira-Filho R A, Sevá-Pereira A, de Magalhães A F

出版信息

Arq Gastroenterol. 1985 Oct-Dec;22(4):172-5.

PMID:3837656
Abstract

Phenotyping of isoniazid acetylators in 19 Caucasoid patients with Gilbert's syndrome was achieved by evaluating the percentual of acetylisoniazid in the urine. The proportion of slow acetylators among the patients with Gilbert's syndrome was similar to those found among Caucasoids of control group. The conclusion was that Gilbert's syndrome doesn't interfere in the hepatic capacity of isoniazid acetylation.

摘要

通过评估尿液中乙酰异烟肼的百分比,对19名患有吉尔伯特综合征的高加索患者进行了异烟肼乙酰化酶表型分析。吉尔伯特综合征患者中慢乙酰化酶的比例与对照组高加索人群中的比例相似。结论是吉尔伯特综合征不会干扰异烟肼乙酰化的肝脏能力。

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