Engel T R, Kowey P R, Wetstein L
Cardiovasc Clin. 1985;16(1):83-96.
Electrophysiologic assessment of ventricular tachyarrhythmias involves the application of paced ectopic beats at the discretion of the cardiologist and not by chance. Because this approach reproducibly induces the sort of symptomatic arrhythmias that are the major cause of death in our country, the procedure has attracted widespread interest. This methodology has accomplished two important alterations in the orientation of physicians to ventricular arrhythmias and sudden death. First, it has turned our focus away from innocent events such as ectopic beats and directed our attention to the architectural and electrophysiologic abnormalities that are the structural substrate for tachyarrhythmias. Second, it has taught us that malignant arrhythmias and sudden death can be treated empirically by repeatedly inducing VT under controlled conditions until a treatment is found. The physiologic and pharmacologic insight obtained with these early experiences will hopefully enable us to treat patients without the need for producing potentially lethal arrhythmias.
室性快速性心律失常的电生理评估需要心脏病专家酌情施加起搏异位搏动，而非随机进行。由于这种方法能够可重复性地诱发那些在我国是主要死亡原因的症状性心律失常，该程序已引起广泛关注。这种方法在医生对室性心律失常和猝死的认识方向上带来了两个重要改变。首先，它使我们的关注点从诸如异位搏动等无害事件上转移开，将注意力引导至作为快速性心律失常结构基础的解剖和电生理异常上。其次，它让我们明白，在可控条件下反复诱发室性心动过速直至找到治疗方法，恶性心律失常和猝死可以凭经验进行治疗。通过这些早期经验获得的生理和药理学见解有望使我们能够在无需诱发潜在致命性心律失常的情况下治疗患者。
