Mays M B, Nguyen H T, Wolf E D, Samuelson D A, Bromberg N M
J Comp Pathol. 1985 Apr;95(2):217-25. doi: 10.1016/0021-9975(85)90008-8.
A slow-growing xanthomatous tumour which diffusely infiltrated the iris and ciliary body of a dog was composed of large, pale, vacuolated cells which contained scattered fine pigment granules. Electron microscopy revealed coalescing vacuoles, lamellar membranous structures, and small groups of melanosomes in the cytoplasm, suggesting melanocytic origin. The lesion resembled balloon cell melanoma of the ciliary body of man. The behaviour of the tumour was benign. This is a clinical and pathological entity which has not been reported previously in the dog.
一只犬的虹膜和睫状体被一种生长缓慢的黄色瘤样肿瘤弥漫性浸润,该肿瘤由大的、淡染的、含空泡的细胞组成,细胞内含有散在的细小色素颗粒。电子显微镜检查显示细胞质中有融合的空泡、板层膜结构和小群黑素体,提示其起源于黑素细胞。该病变类似于人类睫状体的气球状细胞黑色素瘤。肿瘤的行为是良性的。这是一种临床和病理实体,此前在犬中尚未见报道。