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综合脊柱结核评分:胸腰椎脊柱结核管理的临床指南

Comprehensive Spinal Tuberculosis Score: A Clinical Guide for the Management of Thoracolumbar Spinal Tuberculosis.

作者信息

Sonawane Dhiraj Vithal, Kolur Shivaprasad Sharangouda, Pawar Harish Kacharu, Chandanwale Ajay, Pawar Eknath, Jawale Sagar Anant, Vaja Tejas Pragji, Nadwi Safiuddin, Patil Maheshwari Basavangouda

机构信息

Department of Orthopaedics, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, India.

Department of Radio-diagnosis, Karnataka Institute of Medical Sciences, Hubballi, India.

出版信息

Asian Spine J. 2024 Feb;18(1):42-49. doi: 10.31616/asj.2023.0169. Epub 2024 Feb 21.

Abstract

STUDY DESIGN

A newly proposed scoring tool was designed to assist in the clinical management of adult thoracolumbar spinal tuberculosis (TB).

PURPOSE

To formulate a comprehensive yet simple scoring tool to guide decision-making in the management of adult thoracolumbar spinal TB.

OVERVIEW OF LITERATURE

Spine surgeons have differing consensus in defining the threshold grade for clinico-radiological parameters when deciding between operative or conservative treatment for adult thoracolumbar spinal TB. Currently, the void in decision-making from the lack of well-defined guidelines is compensated by the surgeon's experience in treating these patients. To the best of our knowledge, no scoring system holistically integrates multiple facets of spinal TB to guide clinical decision-making.

METHODS

The RAND/University of California, Los Angeles appropriateness method was employed among an expert panel of 10 spine surgeons from four apex tertiary care centers. Vital characteristics that independently influenced treatment decisions in spinal TB were identified, and a scoring tool was formulated. Points were assigned for each component based on their severity. The cutoff scores to guide clinical management were determined from the receiver operating characteristic curve based on the retrospective records of 151 patients treated operatively or non-operatively with improved functional outcomes at the 1-year follow-up.

RESULTS

The components of the comprehensive spinal TB score (CSTS) are pain, kyphosis angle, vertebral destruction, and neurological status. A score classification of <5.5, 5.5-6.5, and >6.5 was established to guide the patient toward conservative, conservative/ operative, and operative management, respectively.

CONCLUSIONS

The CSTS was designed to reflect the essential indicators of mechanical stability, neurological stability, and disease process stabilization in spinal TB. The scoring tool is devised to be practical and serve as a common language in the spine community to facilitate discussions and decision-making in thoracolumbar spinal TB. The validity, reliability, and reproducibility of this tool must be assessed through multicenter long-term studies.

摘要

研究设计

设计了一种新提出的评分工具,以协助成人胸腰椎脊柱结核(TB)的临床管理。

目的

制定一种全面而简单的评分工具,以指导成人胸腰椎脊柱结核管理中的决策。

文献综述

脊柱外科医生在确定成人胸腰椎脊柱结核手术或保守治疗时临床放射学参数的阈值分级方面存在不同共识。目前,缺乏明确指南导致的决策空白由外科医生治疗这些患者的经验来弥补。据我们所知,尚无评分系统全面整合脊柱结核的多个方面以指导临床决策。

方法

在来自四个顶级三级医疗中心的10名脊柱外科医生组成的专家小组中采用了兰德/加利福尼亚大学洛杉矶分校适宜性方法。确定了独立影响脊柱结核治疗决策的重要特征,并制定了评分工具。根据各组成部分的严重程度为其分配分数。根据151例接受手术或非手术治疗且在1年随访时功能结局改善的患者的回顾性记录,从受试者工作特征曲线确定指导临床管理的临界分数。

结果

综合脊柱结核评分(CSTS)的组成部分为疼痛、后凸角度、椎体破坏和神经状态。分别建立了<5.5、5.5 - 6.5和>6.5的评分分类,以指导患者分别接受保守治疗、保守/手术治疗和手术治疗。

结论

CSTS旨在反映脊柱结核中机械稳定性、神经稳定性和疾病进程稳定性的基本指标。该评分工具设计得很实用,可作为脊柱领域的通用语言,以促进胸腰椎脊柱结核的讨论和决策。必须通过多中心长期研究评估该工具的有效性、可靠性和可重复性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a55/10910135/045700faef4d/asj-2023-0169f1.jpg

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