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后路稳定术与经椎弓根减压术在胸段及胸腰段脊柱结核治疗中的作用:一项回顾性评估

Role of Posterior Stabilization and Transpedicular Decompression in the Treatment of Thoracic and Thoracolumbar TB: A Retrospective Evaluation.

作者信息

D'souza Areena R, Mohapatra Bibhudendu, Bansal Murari L, Das Kalidutta

机构信息

Spine Surgery, Orthopaedics Unit 2, Artemis Hospital, Gurgaon, Haryana.

Spine Surgery-Unit 2, Indian Spinal Injuries Centre, Vasant Kunj, New Delhi, India.

出版信息

Clin Spine Surg. 2017 Dec;30(10):E1426-E1433. doi: 10.1097/BSD.0000000000000498.

Abstract

STUDY DESIGN

A retrospective study.

OBJECTIVE

To evaluate the results of posterior pedicle-screw fixation with transpedicular decompression in 21 cases of thoracic and thoracolumbar spinal tuberculosis (TB) in terms of functional, neurological, and radiologic outcomes.

SUMMARY OF BACKGROUND DATA

Spinal TB is predominantly an anterior disease that can lead to kyphotic deformity. Hence, anterior debridement and fusion was considered as the gold standard. However, with remarkable improvements in chemotherapy regimens and diagnostic tools, it is possible to detect the disease process early and treat them with less radical approaches. In the present study, authors have shown the results of posterior pedicle-screw fixation with transpedicular decompression in thoracic and thoracolumbar spinal TB.

MATERIALS AND METHODS

The study reviewed 21 patients with thoracic or thoracolumbar TB with kyphotic deformity who were operated with posterior pedicle-screw fixation and transpedicular decompression (pus aspiration through a Jamshidi needle) with kyphosis correction for either neurological deficits (11) or intractable pain (10), not responding to at least 4-6 weeks of chemotherapy. Patients with <3 spinal segment involvement, <30 degrees kyphosis, and <50% vertebral body destruction were included in the study.

RESULTS

The mean age of patients was 43.9 years and the mean kyphosis angle at the level of involvement was 21.61±3.72 degrees. Kyphosis improved postoperatively to 5.79±3.48 degrees. The mean follow-up period was 24.09 months, and final kyphosis correction was maintained at 8.74±3.65 degrees. Bony fusion was achieved in 80.5% cases. Eleven patients had neurological deficits, and all of them recovered. All patients had a Visual Analog score improvement from 9.52 to 2.57 postoperatively.

CONCLUSIONS

Posterior stabilization with transpedicular decompression can be considered as a good treatment option for the management of thoracic and thoracolumbar TB in patients with <50% vertebral body destruction and <30-degree kyphosis. It provides rapid relief of instability pain, improvement of neurological deficit, and prevents progression of deformity.

摘要

研究设计

一项回顾性研究。

目的

从功能、神经学和影像学结果方面评估21例胸段及胸腰段脊柱结核患者行后路椎弓根螺钉固定并经椎弓根减压的效果。

背景资料总结

脊柱结核主要是一种前路疾病,可导致后凸畸形。因此,前路清创融合术被视为金标准。然而,随着化疗方案和诊断工具的显著改进,有可能早期发现疾病进程并采用较保守的方法进行治疗。在本研究中,作者展示了胸段及胸腰段脊柱结核行后路椎弓根螺钉固定并经椎弓根减压的结果。

材料与方法

该研究回顾了21例伴有后凸畸形的胸段或胸腰段结核患者,这些患者接受了后路椎弓根螺钉固定和经椎弓根减压(通过Jamshidi针抽吸脓液)并进行了后凸矫正,以治疗神经功能缺损(11例)或顽固性疼痛(10例),这些症状对至少4 - 6周的化疗无反应。纳入研究的患者椎体受累节段<3个、后凸畸形<30度且椎体破坏<50%。

结果

患者的平均年龄为43.9岁,受累节段的平均后凸角度为21.61±3.72度。术后后凸畸形改善至5.79±3.48度。平均随访期为24.09个月,最终后凸矫正维持在8.74±3.65度。80.5%的病例实现了骨融合。11例患者有神经功能缺损,所有患者均康复。所有患者术后视觉模拟评分从9.52改善至2.57。

结论

对于椎体破坏<50%且后凸畸形<30度的胸段及胸腰段结核患者,经椎弓根减压的后路稳定术可被视为一种良好的治疗选择。它能迅速缓解不稳定疼痛,改善神经功能缺损,并防止畸形进展。

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