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钝性与穿透性腹部创伤的临床特征、治疗及短期预后比较:一项多中心回顾性队列研究

Comparison of Clinical Characteristics, Therapy, and Short-Term Prognosis between Blunt and Penetrating Abdominal Trauma: A Multicentric Retrospective Cohort Study.

作者信息

Liu Yi, Gao Yunhe, Chen Zhida, Cui Jianxin, Liang Wenquan, Wang Ze, Sun Linde, Pang Chuan, Lv Yuan, Liu Guoxiao, Lu Tingting, Zhang Gan, Dong Xiaoyu, Xu Hong, Yao Sheng, Liang Feng, Liu Gang, Chen Gang, He Jianmiao, Xu Wentong, Wei Bo, Xi Hongqing, Chen Lin

机构信息

Department of Abdominal Trauma Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.

Department of Gastric Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.

出版信息

Emerg Med Int. 2024 Feb 13;2024:5215977. doi: 10.1155/2024/5215977. eCollection 2024.

Abstract

OBJECTIVE

Large-scale studies on the characteristics and management of abdominal trauma in megacities in China are lacking. The aim of this study was to analyze and present the clinical patterns and treatment status of abdominal trauma in regional medical centers.

METHODS

Cases of abdominal trauma treated at seven medical centers in Beijing from 2010 to 2021 were collected. Clinical information about age, sex, injury cause, geographic distribution, abbreviated injury scale/injury severity score (AIS/ISS) value, injury-hospital time, preoperative time, surgically identified organ injuries, type of surgery, causes of reoperation and 90-day mortality was included in this study. Clinical characteristics, treatment methods, and short-term prognoses (90-days survival) were compared between blunt abdominal trauma (BAT) and penetrating abdominal trauma (PAT) cases. Non-normally distributed data are described as medians (IQR), and the Mann‒Whitney test was performed; qualitative data were analyzed using the test. Univariate and multivariate survival analyses were performed by the Cox proportional hazards model.

RESULTS

A total of 553 patients (86.98% male) with a median age of 36.50 (27.00-48.00) years were included. The BAT group had a significantly higher proportion of serious injury (=0.001), lower initial hemoglobin level (=0.001), and a lower laparoscopy surgery rate (=0.044) compared to the PAT group. Additionally, more BAT cases were from the area around Beijing (=0.008) and a longer injury-regional hospital time (10.47 (5.18-22.51) hours vs. 7.00 (3.80-15.38) hours, =0.001). In the hollow viscus injury subgroup, the BAT group had a significantly longer injury-regional hospital time and preoperative time compared to the PAT group (injury-regional hospital time: 10.23 (6.00-21.59) hours vs. 7.07 (3.99-13.85) hours, =0.002; preoperative time: 3.02 (2.01-5.58) hours vs. 2.81 (1.85-3.63) hours, =0.047). The overall 90-day mortality was 11.9%, and longer injury-regional hospital time (HR: 1.01, 95% CI: 1.00-1.02, =0.008), receipt of ICU treatment (HR: 4.69, 95% CI: 2.54-8.65, =0.001), and severe ISSs (ISS > 25 vs. ISS < 16, HR: 2.78, 95% CI: 1.38-5.601, =0.004) had a worse impact on survival.

CONCLUSION

More patients with BAT were transferred to higher-level hospital, leading to significantly longer prehospital and preoperation time. In the subgroup of hemodynamically stable individuals, more patients with BAT experienced hollow viscus injuries. For those patients, aggressive diagnostic laparoscopic exploration may be beneficial. Patients with longer injury-regional hospital intervals, the need for ICU care, and higher injury severity scores (ISSs) suffered from worse prognoses.

摘要

目的

中国特大城市腹部创伤特征及管理的大规模研究尚缺。本研究旨在分析并呈现区域医疗中心腹部创伤的临床模式及治疗现状。

方法

收集2010年至2021年在北京7家医疗中心接受治疗的腹部创伤病例。本研究纳入了有关年龄、性别、损伤原因、地理分布、简明损伤定级/损伤严重度评分(AIS/ISS)值、受伤至医院时间、术前时间、手术确定的器官损伤、手术类型、再次手术原因及90天死亡率的临床信息。比较钝性腹部创伤(BAT)和穿透性腹部创伤(PAT)病例的临床特征、治疗方法及短期预后(90天生存率)。非正态分布数据以中位数(IQR)描述,并进行曼-惠特尼检验;定性数据采用检验分析。采用Cox比例风险模型进行单因素和多因素生存分析。

结果

共纳入553例患者(男性占86.98%),中位年龄为36.50(27.00 - 48.00)岁。与PAT组相比,BAT组重伤比例显著更高(=0.001),初始血红蛋白水平更低(=0.001),腹腔镜手术率更低(=0.044)。此外,更多BAT病例来自北京周边地区(=0.008),且受伤至区域医院时间更长(10.47(5.18 - 22.51)小时 vs. 7.00(3.80 - 15.38)小时,=0.001)。在中空脏器损伤亚组中,与PAT组相比,BAT组受伤至区域医院时间和术前时间显著更长(受伤至区域医院时间:10.23(6.00 - 21.59)小时 vs. 7.07(3.99 - 13.85)小时,=0.002;术前时间:3.02(2.01 -

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b45/10878762/77386baa93f4/EMI2024-5215977.001.jpg

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