Int J Oral Maxillofac Implants. 2024 Oct 16;39(5):699-706. doi: 10.11607/jomi.10759.
To evaluate the influence of immediate loading on the osseointegration and bone density of implants placed in a healed alveolar bone crest and supporting single crowns.
Two solid titanium transmucosal miniimplants were placed in the distal regions of the mandible in 14 patients. One mini-implant was immediately functionally loaded, whereas the other was left unloaded. After 2 months of healing, biopsy samples were retrieved and the levels of new bone, old bone, and total bone (new + old) were assessed.
Histologic examination was performed on biopsies from 12 patients (n = 12). The new bone-to-implant contact percentage (BIC%) was 40.3% ± 16.8% and 55.1% ± 19.1% (P = .043) at the unloaded and loaded sites, respectively; in addition, the total BIC% was 44.9% ± 17.0% and 59.5% ± 18.8%, respectively (P = .034). The new bone density was 45.9% ± 11.6% for the unloaded implants and 45.9% ± 16.7% for the loaded implants (P = .622).
Immediate loading had a positive effect on bone apposition at the implant surface, but no effect on bone density was observed after 2 months of healing.
评估即刻负载对愈合牙槽嵴中植入物的骨整合和骨密度的影响，以支持单冠。
将两个实心钛经粘膜迷你植入物放置在下颌骨的远侧区域，共 14 名患者。一个迷你植入物被立即功能性加载，而另一个未加载。愈合 2 个月后，取出活检样本，评估新骨、旧骨和总骨（新骨+旧骨）的水平。
对 12 名患者（n=12）的活检进行了组织学检查。未加载和加载部位的新骨-种植体接触百分比（BIC%）分别为 40.3%±16.8%和 55.1%±19.1%（P=0.043）；此外，总 BIC%分别为 44.9%±17.0%和 59.5%±18.8%（P=0.034）。未加载种植体的新骨密度为 45.9%±11.6%，加载种植体的新骨密度为 45.9%±16.7%（P=0.622）。
即刻负载对种植体表面的骨沉积有积极影响，但在愈合 2 个月后，对骨密度没有影响。
