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精神障碍患者早期反应与身心康复结局的关联及其与治疗和疾病信念的联系——一项前瞻性纵向队列研究

The association of early response with the outcome of psychosomatic rehabilitation in patients with mental disorders and its link to treatment and illness beliefs-A prospective longitudinal cohort study.

作者信息

von der Warth Rieka, Rudolph Matthias, Bengel Jürgen, Glattacker Manuela

机构信息

Section of Health Care Research and Rehabilitation Research, Institute of Medical Biometry and Statistics, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Deutsche Rentenversicherung Rheinland-Pfalz (German Statutory Pension Insurance Rhineland Palatinate), Mittelrhein-Klinik (Clinic for Psychosomatic Rehabilitation), Boppard-Bad Salzig, Germany.

出版信息

Psychother Res. 2025 Mar;35(3):379-394. doi: 10.1080/10503307.2024.2316014. Epub 2024 Feb 21.

DOI:10.1080/10503307.2024.2316014
PMID:38381978
Abstract

Early response is considered to be an important predictor for therapy outcomes; yet little is known about its relevance in psychosomatic rehabilitation. This paper aims to describe the association of early response in psychosomatic rehabilitation, as well as the associations of early response with pre-rehabilitative factors such as illness and treatment beliefs. A longitudinal study with three measurement points was applied. Early response was defined using the percent improvement method after two weeks of treatment. Its association with therapy outcome and with illness and treatment beliefs was analyzed using multiple regression analyses. A total of 264 participants took part. Early response was a significant predictor of psychosomatic rehabilitation outcome, explaining an incremental variance of 1-30% after controlling for initial symptom burden. Illness and treatment beliefs predicted 6-20% variance in early response. Important illness beliefs referred to perceived symptoms, consequences and comprehensibility of the illness. Important treatment beliefs referred to expectations about rehabilitation structure, processes and concerns. Early response is associated with the therapy outcome of psychosomatic rehabilitation, with illness and treatment beliefs found to be associated with early response. Further research on the predictors of early response in psychosomatic rehabilitation is needed.

摘要

早期反应被认为是治疗结果的重要预测指标;然而,其在身心康复中的相关性却鲜为人知。本文旨在描述身心康复中早期反应的关联,以及早期反应与诸如疾病和治疗信念等康复前因素的关联。采用了一项有三个测量点的纵向研究。早期反应通过治疗两周后的改善百分比方法来定义。使用多元回归分析来分析其与治疗结果以及与疾病和治疗信念的关联。共有264名参与者。早期反应是身心康复结果的显著预测指标,在控制初始症状负担后解释了1%至30%的增量方差。疾病和治疗信念预测了早期反应中6%至20%的方差。重要的疾病信念涉及对疾病症状、后果和可理解性的感知。重要的治疗信念涉及对康复结构、过程和关注点的期望。早期反应与身心康复的治疗结果相关,疾病和治疗信念与早期反应相关。需要对身心康复中早期反应的预测因素进行进一步研究。

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