Keen M E, Engstrand D A, Hafez G R
Arch Pathol Lab Med. 1985 Jan;109(1):70-2.
Two cases of unsuspected veno-occlusive disease of the liver were discovered at autopsy. Nearly all central veins and sublobular venules were occluded by lipogranulomas consisting of lipid-laden macrophages, epithelioid histiocytes, giant cells, fibroblasts, lymphocytes, and deposits of collagen. The process extended into the sublobular hepatic venules. Large hepatic veins were uninvolved. Known causes of veno-occlusive disease were ruled out, and the cause of the present cases is unknown.
尸检发现两例未被怀疑的肝静脉闭塞性疾病。几乎所有中央静脉和小叶下静脉均被脂肉芽肿阻塞，脂肉芽肿由富含脂质的巨噬细胞、上皮样组织细胞、巨细胞、成纤维细胞、淋巴细胞和胶原沉积物组成。该病变扩展至小叶下肝静脉。大的肝静脉未受累。已知的肝静脉闭塞性疾病病因均被排除，目前病例的病因不明。
