Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, Anhui, China.
Department of Sports Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, Yunnan, China.
Sci Rep. 2024 Feb 22;14(1):4342. doi: 10.1038/s41598-024-55055-z.
Surgical intervention is typically recommended for thoracic ossification of the ligamentum flavum (TOLF). This study aimed to evaluate the efficacy and safety of a novel non-coaxial one-hole split endoscope (OSE) technique for treating TOLF. We performed OSE procedure on 13 patients with TOLF from June 2022 to July 2023. The mean operative time was 117.5 ± 15.4 min. VAS scores for lower limbs decreased from 6.5 ± 0.8 preoperative to 1.6 ± 0.4 at the last follow-up (P < 0.001). ODI scores improved from 62.4 ± 5.7 preoperative to 18.6 ± 2.2 at the last follow-up (P < 0.001), and mJOA scores increased from 5.1 ± 1.6 preoperative to 8.4 ± 1.5 at the latest follow-up (P < 0.001). All patients achieved ASIA scale grade D or E at the final follow-up, except for two patients remained residual limb numbness. None of the thirteen patients suffered from severe perioperative complications. The OSE technique proves to be a safe and effective procedure for treating TOLF or even with dura mater ossification, characterized by minimal surgical trauma, relatively smooth learning curve and flexible operation.
手术干预通常被推荐用于治疗胸段黄韧带骨化(TOLF)。本研究旨在评估一种新型非同轴单孔分体式内窥镜(OSE)技术治疗 TOLF 的疗效和安全性。我们对 2022 年 6 月至 2023 年 7 月的 13 例 TOLF 患者进行了 OSE 手术。平均手术时间为 117.5±15.4 分钟。下肢 VAS 评分从术前的 6.5±0.8 分降至末次随访时的 1.6±0.4 分(P<0.001)。ODI 评分从术前的 62.4±5.7 分改善至末次随访时的 18.6±2.2 分(P<0.001),mJOA 评分从术前的 5.1±1.6 分提高至末次随访时的 8.4±1.5 分(P<0.001)。所有患者在末次随访时均达到 ASIA 分级 D 或 E,除 2 例患者仍有下肢麻木残留外,无 13 例患者发生严重围手术期并发症。OSE 技术治疗 TOLF 甚至伴有硬脊膜骨化,具有手术创伤小、学习曲线相对平稳、操作灵活等特点,是一种安全有效的手术方法。