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口腔潜在恶性疾病和口腔鳞状细胞癌的流行情况及相关因素:一项机构研究。

Prevalence and factors associated with oral potentially malignant disorders and oral squamous cell carcinoma: An institutional study.

机构信息

Department of Oral Medicine and Radiology, Government Dental College and Hospital, Ahmedabad, Gujarat, India.

出版信息

J Cancer Res Ther. 2023 Jan 1;19(Suppl 2):S536-S544. doi: 10.4103/jcrt.jcrt_759_22. Epub 2023 Mar 28.

Abstract

INTRODUCTION

Incidence & prevalence of OPMDs & OSCC is increasing day by day, thereby escalating the burden of oral cancer in India. Oral cancer ranks in the top three of all cancers in India and is quickly becoming a health priority. This study aims to assess prevalence and associated factors of OPMDs and OSCC in patients attending dental OPD and its association with age, gender, habit (type & duration), clinical presentation and site of involvement.

MATERIAL AND METHODS

A prospectively 12 months study was conducted in the outpatient department. Patient's data whether suspected or proven cases of OPMDs & OSCC and fits in clinical criteria were reviewed and analysed for demographic data, oral adverse habit, clinical presentation and site of involvement.

RESULTS

Overall 38,588 patient's data were analysed for 12 month time duration. Out of this 552 (1.43%) cases of OPMDs and 58 (0.15%) cases of OSCC were reported. Out of 552 maximum patients were reported with OSMF (34.4%), followed by other lesions and minimum with LP (7.9%). Age group most commonly affected was above 45 years (44.9%) of age. Males (81.1%) were affected more than females. OPMDs (92%) and OSCC (96.5%) were mostly associated with smokeless or smoking form of tobacco.

CONCLUSION

Present study evaluated the prevalence rates and associated factors of OPMDs & OSCC, which is beneficial for general practitioner in early diagnosis, formulating better treatment plan and to educate general population about risk factors, early signs and symptoms of these lesions.

摘要

简介

口腔黏膜潜在恶性疾病(OPMDs)和口腔鳞状细胞癌(OSCC)的发病率和患病率日益增加,从而使印度的口腔癌负担加重。口腔癌在印度所有癌症中排名前三位,并且正在迅速成为一个健康重点。本研究旨在评估口腔门诊患者中 OPMDs 和 OSCC 的患病率和相关因素,以及其与年龄、性别、习惯(类型和持续时间)、临床表现和受累部位的关系。

材料和方法

本前瞻性研究持续了 12 个月,在口腔门诊进行。对疑似或确诊为 OPMDs 和 OSCC 的患者数据进行了回顾性分析,并对人口统计学数据、口腔不良习惯、临床表现和受累部位进行了分析。

结果

在 12 个月的时间内,共分析了 38588 名患者的数据。其中,552 例(1.43%)为 OPMDs 病例,58 例(0.15%)为 OSCC 病例。在 552 例 OPMDs 中,最常见的是口腔黏膜下纤维化(OSMF)(34.4%),其次是其他病变,最少的是白斑(LP)(7.9%)。年龄组中最常见的是 45 岁以上(44.9%)。男性(81.1%)比女性(18.9%)更容易受到影响。OPMDs(92%)和 OSCC(96.5%)主要与无烟或吸烟形式的烟草有关。

结论

本研究评估了 OPMDs 和 OSCC 的患病率和相关因素,这对全科医生进行早期诊断、制定更好的治疗计划以及对普通人群进行有关这些病变的危险因素、早期症状和体征的教育都有帮助。

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