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一例年轻男性口咽鳞癌患者在完成放化疗后出现罕见的腹膜转移。

A rare case of peritoneal metastases from oropharyngeal squamous cell carcinoma in a young male after completion of chemoradiotherapy.

机构信息

Department of Radiodiagnosis, Adesh Medical College and Hospital, Ambala, Haryana, India.

Department of Radiodiagnosis, MMIMSR, Mullana, Haryana, India.

出版信息

J Cancer Res Ther. 2023 Jan 1;19(Suppl 2):S954-S957. doi: 10.4103/jcrt.jcrt_163_22. Epub 2023 Apr 29.

DOI:10.4103/jcrt.jcrt_163_22
PMID:38384089
Abstract

Distant metastases are frequent in head and neck squamous cell carcinomas (HNSCC), but they are limited to some organs like lungs, bone, mediastinum, liver and brain. Peritoneal metastases (PMs) from HNSCC are extremely rare. A 28-year-old chronic smoker and alcoholic was diagnosed with squamous cell carcinoma of oropharynx. Patient was admitted and was given six cycles of concurrent chemo and radiotherapy (CCRT) and was discharged. Two months later, he presented with abdominal pain and lump. Contrast-enhanced CT revealed ascites, peritoneal implants and subcutaneous deposit which were proved to be metastases by histopathology. The present case is the seventh reported case of PM from HNSCC. • Patients of HNSCC shall be screened for distant metastases. • Differential diagnosis of HNSCC needs consideration when encountered with peritoneal metastases. • Research is required to understand the basis of PM in HNSCC while on CCRT to suggest management modifications.

摘要

远处转移在头颈部鳞状细胞癌(HNSCC)中很常见,但仅限于某些器官,如肺、骨、纵隔、肝和脑。HNSCC 的腹膜转移(PM)极为罕见。一名 28 岁的慢性吸烟者和酗酒者被诊断为口咽鳞状细胞癌。患者住院并接受了六周期的同期化疗和放疗(CCRT),然后出院。两个月后,他出现腹痛和肿块。增强 CT 显示腹水、腹膜种植和皮下沉积物,组织病理学证实为转移。本病例是第七例 HNSCC 的 PM 报道病例。

  1. HNSCC 患者应进行远处转移筛查。

  2. 遇到腹膜转移时,需要考虑 HNSCC 的鉴别诊断。

  3. 需要进行研究,以了解 CCRT 期间 HNSCC 中 PM 的基础,从而提出管理修改建议。

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