Lai Yongkang, Zhang Qian, Liao Foqiang, Pan Xiaolin, Zhu Zhenhua, Long Shunhua, Zhou Xiaojiang, Li Guohua, Zhu Yin, Chen Youxiang, Shu Xu
Department of Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, 330006, China.
Department of Gastroenterology, Ganzhou People's Hospital, Jiangxi Medical College, Nanchang University, Ganzhou, Jiangxi, 341000, China.
Heliyon. 2024 Feb 7;10(4):e25748. doi: 10.1016/j.heliyon.2024.e25748. eCollection 2024 Feb 29.
Fever is one of the postoperative complications of endoscopic submucosal dissection (ESD) and its derivative technology. However, there are few studies on risk factors for fever after ESD and its derivative technology. The aim of this study was to determine the incidence and related risk factors after ESD and its derivative technology for gastric lesions.
A retrospective review of patients with gastric lesions who were treated by ESD and its derivative technology in our hospital from January 2014 to January 2019 was conducted.
A total of 1955 patients were included in the present study. A total of 451 (23.1 %) patients presented with fever after ESD and its derived techniques. The highest fever temperature was 37.6 ± 3.12 °C, and the number of days with fever was 1.48 ± 0.85. Through single factor and multiple factor analysis, age (OR: 1.261, 95% CI: 1.009-1.576, p < 0.05), procedure time (OR: 1.457, 95% CI: 1.053-2.016, p < 0.05), postoperative gastric tube placement (OR: 2.098, 95% CI: 1:616-2.723, p < 0.05), intraoperative hemorrhage (OR: 1.537, 95% CI: 1.196-1.974, p < 0.05) and perforation (OR: 1.970, 95% CI: 1.531-2.535, p < 0.05) were independent risk factors for postoperative fever.
Age ≥56 years old, procedure time ≥60 min, gastric tube placement, intraoperative hemorrhage and perforation were independent risk factors for postoperative fever after gastric ESD and its derivative technology. Attention should be given to such patients to minimize the risk of postoperative fever.
发热是内镜黏膜下剥离术（ESD）及其衍生技术的术后并发症之一。然而，关于ESD及其衍生技术后发热的危险因素的研究较少。本研究的目的是确定ESD及其衍生技术治疗胃病变后的发生率及相关危险因素。
对2014年1月至2019年1月在我院接受ESD及其衍生技术治疗的胃病变患者进行回顾性研究。
本研究共纳入1955例患者。共有451例（23.1%）患者在ESD及其衍生技术后出现发热。最高发热温度为37.6±3.12℃，发热天数为1.48±0.85天。通过单因素和多因素分析，年龄（OR：1.261，95%CI：1.009 - 1.576，p<0.05）、手术时间（OR：1.457，95%CI：1.053 - 2.016，p<0.05）、术后放置胃管（OR：2.098，95%CI：1.616 - 2.723，p<0.05）、术中出血（OR：1.537，95%CI：1.196 - 1.974，p<0.05）和穿孔（OR：1.970，95%CI：1.531 - 2.535，p<0.05）是术后发热的独立危险因素。
年龄≥56岁、手术时间≥60分钟、放置胃管、术中出血和穿孔是胃ESD及其衍生技术后术后发热的独立危险因素。应关注此类患者，以尽量降低术后发热风险。
