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肠易激综合征(IBS):我们能否找出背后的原因?

Irritable bowel syndrome (IBS): could we decide what is behind?

机构信息

Institute of Health Promotion and Sport Sciences, Faculty of Education and Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.

出版信息

Biol Futur. 2024 Mar;75(1):61-71. doi: 10.1007/s42977-024-00205-7. Epub 2024 Feb 22.

DOI:10.1007/s42977-024-00205-7
PMID:38386191
Abstract

Functional visceral problems are frequently present nowadays in the medical practice probably due to the significant mental and emotional load on people. Although physicians and psychophysiologists are active on the field, still we are far from a complete knowledge, despite the fact that scientists like the Hungarian Professor György Ádám already had initiated a new approach called visceral psychophysiology already a long time ago. In this article, we commemorate Professor Ádám by analyzing one of the most frequent functional disorders, irritable bowel syndrome (IBS), calling psychophysiology for help. First, we try to give a definition, then show the general descriptions and characteristics of IBS. Factors like stress, gender, and gastrointestinal pain are followed by the potential role of the immune system and the neuronal factors as well as the supposed brain mechanisms. We hope that this overview of the IBS-history would show how significant scientists can be decisive in certain fields of the science and practice.

摘要

如今,功能性内脏问题在医学实践中经常出现,这可能是由于人们承受着巨大的精神和情绪压力。尽管医生和心理生理学家在这一领域很活跃,但尽管像匈牙利教授 György Ádám 这样的科学家很久以前就已经提出了一种叫做内脏心理生理学的新方法,但我们仍然远未完全了解这一问题。在本文中,我们通过分析最常见的功能性疾病之一——肠易激综合征 (IBS),并求助于心理生理学,来纪念 Ádám 教授。首先,我们试图给出一个定义,然后展示 IBS 的一般描述和特征。接着是压力、性别和胃肠道疼痛等因素,然后是免疫系统和神经元因素以及假设的大脑机制的潜在作用。我们希望通过对 IBS 历史的概述,展示出科学家在科学和实践的某些领域可以起到多么重要的决定性作用。

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1
Irritable bowel syndrome (IBS): could we decide what is behind?肠易激综合征(IBS):我们能否找出背后的原因?
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2
Functional Bowel Disorders.功能性肠病
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3
Abdominal pain in Irritable Bowel Syndrome: a review of putative psychological, neural and neuro-immune mechanisms.肠易激综合征的腹痛:潜在心理、神经和神经免疫机制的综述。
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Cognitive behavioral therapy for irritable bowel syndrome: the effects on state and trait anxiety and the autonomic nervous system during induced rectal distensions - An uncontrolled trial.肠易激综合征的认知行为疗法:诱导直肠扩张期间对状态和特质焦虑及自主神经系统的影响——一项非对照试验。
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[Psychosocial factors and visceral hypersensitivity in irritable bowel syndrome].[心理社会因素与肠易激综合征的内脏高敏感性]
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Recent advances in pharmacological treatment of irritable bowel syndrome.肠易激综合征药物治疗的最新进展
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本文引用的文献

1
The role of psychological factors in functional gastrointestinal disorders: a systematic review and meta-analysis.心理因素在功能性胃肠病中的作用:系统评价和荟萃分析。
Int J Colorectal Dis. 2023 Mar 9;38(1):65. doi: 10.1007/s00384-023-04333-9.
2
Factors influencing rectal hypersensitivity in irritable bowel syndrome: A systematic review and meta-analysis.影响肠易激综合征直肠超敏反应的因素:一项系统评价和荟萃分析。
Neurogastroenterol Motil. 2023 Apr;35(4):e14515. doi: 10.1111/nmo.14515. Epub 2022 Dec 26.
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Assessing the Impact of Changes to the Rome IV Criteria for Clinical Practice in Irritable Bowel Syndrome.
评估罗马IV标准变化对肠易激综合征临床实践的影响。
Gastroenterology. 2022 May;162(6):1752-1754.e1. doi: 10.1053/j.gastro.2022.01.021. Epub 2022 Jan 22.
4
A Rome Working Team Report on Brain-Gut Behavior Therapies for Disorders of Gut-Brain Interaction.罗马工作组关于脑-肠行为疗法治疗肠-脑相互作用障碍的报告。
Gastroenterology. 2022 Jan;162(1):300-315. doi: 10.1053/j.gastro.2021.09.015. Epub 2021 Sep 14.
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Behavioral Strategies for Irritable Bowel Syndrome: Brain-Gut or Gut-Brain?肠易激综合征的行为策略:脑-肠还是肠-脑?
Gastroenterol Clin North Am. 2021 Sep;50(3):581-593. doi: 10.1016/j.gtc.2021.03.006. Epub 2021 Jun 25.
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Functional gastrointestinal disorders in inflammatory bowel disease: Time for a paradigm shift?炎症性肠病中的功能性胃肠病:是时候改变观念了?
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Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis.根据罗马 III 或 IV 标准,全球肠易激综合征的患病率:系统评价和荟萃分析。
Lancet Gastroenterol Hepatol. 2020 Oct;5(10):908-917. doi: 10.1016/S2468-1253(20)30217-X. Epub 2020 Jul 20.
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The association of different interoceptive dimensions with functional gastrointestinal symptoms.不同内脏感知维度与功能性胃肠症状的关联。
J Health Psychol. 2021 Dec;26(14):2801-2810. doi: 10.1177/1359105320929426. Epub 2020 Jun 15.
10
The Rome IV: Irritable bowel syndrome - A functional disorder.罗马 IV 标准:肠易激综合征 - 一种功能性障碍。
Best Pract Res Clin Gastroenterol. 2019 Jun-Aug;40-41:101634. doi: 10.1016/j.bpg.2019.101634. Epub 2019 Jul 18.