From the Departments of Nuclear Medicine, Centre Hospitalier Universitaire Angers, Angers, France.
Centre Hospitalier du Mans, Le Mans, France.
Clin Nucl Med. 2024 May 1;49(5):e206-e207. doi: 10.1097/RLU.0000000000005135. Epub 2024 Feb 22.
Gamma/delta T-cell lymphoma is a rare and aggressive subtype of primary cutaneous lymphoma. Clinical manifestations typically include the development of subcutaneous nodules and ulcerated plaques. Some forms present as panniculitis with hemophagocytic syndrome. Prognosis is bleak, with a 10% 5-year survival rate. In this report, we present the case of a 20-year-old man from French Polynesia, referred for 18 F-FDG PET/CT because of the progressive worsening of febrile cutaneous-mucosal infiltration on the face persisting for 1 month. PET examination guided a biopsy from the right deltoid muscle, and expert histological analysis confirmed a CD8 + not otherwise specified T-cell lymphoma, granzyme+ and TCR gamma/delta.
γ/δ T 细胞淋巴瘤是一种罕见且侵袭性强的原发性皮肤淋巴瘤亚型。临床表现通常包括皮下结节和溃疡性斑块的形成。某些类型表现为伴有噬血细胞综合征的脂膜炎。预后较差，5 年生存率为 10%。本报告介绍了一位来自法属波利尼西亚的 20 岁男性患者，因面部发热性皮肤黏膜浸润持续 1 个月逐渐加重而转诊进行 18 F-FDG PET/CT 检查。PET 检查引导右三角肌活检，专家组织学分析证实为 CD8+未特指 T 细胞淋巴瘤，颗粒酶+和 TCR γ/δ阳性。
