Department for Trauma and Orthopaedic Surgery, Cologne-Merheim Medical Center (CMMC).
Institute for Research in Operative Medicine (IFOM), Witten/Herdecke University, Campus Cologne-Merheim, Cologne, Germany.
Curr Opin Anaesthesiol. 2024 Apr 1;37(2):110-116. doi: 10.1097/ACO.0000000000001346. Epub 2024 Jan 22.
The diagnosis and treatment of patients with severe traumatic bleeding and subsequent trauma-induced coagulopathy (TIC) is still inconsistent, although the implementation of standardized algorithms/treatment pathways was repeatedly linked to improved outcome. Various evidence-based guidelines for these patients now exist, three of which have recently been updated.
A synopsis of the three recently updated guidelines for diagnosis and treatment of seriously bleeding trauma patients with TIC is presented: (i) AWMF S3 guideline 'Polytrauma/Seriously Injured Patient Treatment' under the auspices of the German Society for Trauma Surgery; (ii) guideline of the European Society of Anesthesiology and Intensive Care (ESAIC) on the management of perioperative bleeding; and (iii) European guideline on the management of major bleeding and coagulopathy after trauma in its 6th edition (EU-Trauma).
Treatment of trauma-related bleeding begins at the scene with local compression, use of tourniquets and pelvic binders and rapid transport to a certified trauma centre. After arrival at the hospital, measures to record, monitor and support coagulation function should be initiated immediately. Surgical bleeding control is carried out according to 'damage control' principles. Modern coagulation management includes individualized treatment based on target values derived from point-of-care viscoelastic test procedures.
严重创伤出血及由此引发的创伤性凝血病(TIC)患者的诊疗仍不一致,尽管标准化算法/治疗流程的实施与改善预后反复相关。目前存在针对这些患者的各种循证指南,其中有 3 个最近已更新。
概述了最近更新的 3 个严重创伤伴 TIC 出血患者诊疗指南:(i)德国创伤外科学会(AWMF)支持下的“多发创伤/严重受伤患者治疗”S3 指南;(ii)欧洲麻醉学会和重症监护医学学会(ESAIC)关于围手术期出血管理的指南;(iii)创伤后大出血和凝血障碍管理的欧洲指南,第 6 版(EU-Trauma)。
创伤相关出血的治疗始于现场的局部压迫、使用止血带和骨盆约束带以及快速转运至认证创伤中心。到达医院后,应立即启动记录、监测和支持凝血功能的措施。根据“损伤控制性”原则进行外科止血控制。现代凝血管理包括基于即时检测黏弹性试验程序得出的目标值的个体化治疗。