Wu Kevin Y, Fujioka Jamie K, Daigle Patrick, Tran Simon D
Department of Surgery, Division of Ophthalmology, University of Sherbrooke, Sherbrook, QC J1G 2E8, Canada.
Faculty of Medicine, Queen's University, Kingston, ON K7L 3N6, Canada.
J Funct Biomater. 2024 Jan 29;15(2):33. doi: 10.3390/jfb15020033.
The integration of functional biomaterials in oculoplastic and orbital surgery is a pivotal area where material science and clinical practice converge. This review, encompassing primary research from 2015 to 2023, delves into the use of biomaterials in two key areas: the reconstruction of orbital floor fractures and the development of implants and prostheses for anophthalmic sockets post-eye removal. The discussion begins with an analysis of orbital floor injuries, including their pathophysiology and treatment modalities. It is noted that titanium mesh remains the gold standard for orbital floor repair due to its effectiveness. The review then examines the array of materials used for orbital implants and prostheses, highlighting the dependence on surgeon preference and experience, as there are currently no definitive guidelines. While recent innovations in biomaterials show promise, the review underscores the need for more clinical data before these new materials can be widely adopted in clinical settings. The review advocates for an interdisciplinary approach in orbital surgery, emphasizing patient-centered care and the potential of biomaterials to significantly enhance patient outcomes.
功能性生物材料在眼整形与眼眶外科中的整合是材料科学与临床实践交汇的关键领域。本综述涵盖了2015年至2023年的主要研究,深入探讨了生物材料在两个关键领域的应用:眶底骨折的修复以及眼球摘除后无眼球眼眶植入物和假体的研发。讨论首先分析了眶底损伤,包括其病理生理学和治疗方式。值得注意的是,钛网因其有效性仍然是眶底修复的金标准。该综述接着研究了用于眼眶植入物和假体的一系列材料,强调了目前由于缺乏明确指南,对材料的选择依赖于外科医生的偏好和经验。虽然生物材料的最新创新显示出前景,但该综述强调在这些新材料能够在临床环境中广泛应用之前,需要更多的临床数据。该综述主张在眼眶外科中采用跨学科方法,强调以患者为中心的护理以及生物材料显著改善患者治疗效果的潜力。