Standfast H A, Muller M J, Wilson D D
Prog Clin Biol Res. 1985;178:611-6.
Adult female Culicoides brevitarsis Kieffer, important vectors of arboviruses affecting livestock in Australia, were fed on penned Hereford yearling cattle which had been given a single subcutaneous injection of ivermectin at a dose of 200 mcg/kg. The mean mortality of engorged females 48 hr after feeding on the treated cattle was 99% for 10 days posttreatment and in excess of 40% for 18 days posttreatment. Based on these results, it appears that ivermectin administered subcutaneously could be a useful tool for the control of Culicoides-transmitted diseases and would provide an attractive alternative to "slaughter out" programs in the case of a major exotic disease threat.
成年雌性短角库蠓（Culicoides brevitarsis Kieffer）是澳大利亚影响家畜的虫媒病毒的重要传播媒介，以圈养的一岁赫里福德牛为食，这些牛已皮下注射了剂量为200微克/千克的伊维菌素。取食经处理牛后48小时饱血雌蠓的平均死亡率在处理后10天为99%，处理后18天超过40%。基于这些结果，皮下注射伊维菌素似乎可能是控制库蠓传播疾病的有用工具，并且在面临重大外来疾病威胁时，将为“全部屠宰”计划提供有吸引力的替代方案。
