Ubinha Ana Carla Franco, Pedrão Priscila Grecca, Tadini Aline Cássia, Schmidt Ronaldo Luis, Santos Marcelo Henrique Dos, Andrade Carlos Eduardo Mattos da Cunha, Longatto Filho Adhemar, Reis Ricardo Dos
Department of Gynecologic Oncology, Barretos Cancer Hospital, São Paulo 14784-400, Brazil.
Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo 14784-400, Brazil.
Cancers (Basel). 2024 Feb 18;16(4):817. doi: 10.3390/cancers16040817.
Pelvic exenteration represents a radical procedure aimed at achieving complete tumor resection with negative margins. Although it is the only therapeutic option for some cases of advanced tumors, it is associated with several perioperative complications. We believe that careful patient selection is related to better oncologic outcomes and lower complication rates. The objectives of this review are to identify the most current indications for this intervention, suggest criteria for case selection, evaluate recommendations for perioperative care, and review oncologic outcomes and potential associated complications. To this end, an analysis of English language articles in PubMed was performed, searching for topics such as the indication for pelvic exenteration for recurrent gynecologic neoplasms selection of oncologic cases, the impact of tumor size and extent on oncologic outcomes, preoperative and postoperative surgical management, surgical complications, and outcomes of overall survival and recurrence-free survival.
盆腔脏器清除术是一种根治性手术，旨在实现肿瘤的完全切除且切缘阴性。尽管它是某些晚期肿瘤病例的唯一治疗选择，但它与多种围手术期并发症相关。我们认为，仔细的患者选择与更好的肿瘤学结局和更低的并发症发生率相关。本综述的目的是确定该干预措施的最新适应证，提出病例选择标准，评估围手术期护理建议，并回顾肿瘤学结局及潜在相关并发症。为此，我们对PubMed上的英文文章进行了分析，搜索了诸如复发性妇科肿瘤盆腔脏器清除术的适应证、肿瘤病例的选择、肿瘤大小和范围对肿瘤学结局的影响、术前和术后手术管理、手术并发症以及总生存和无复发生存结局等主题。
