Gyokova Elitsa, Hristova-Atanasova Eleonora, Iskrov Georgi
Department of Obstetrics and Gynecology, Faculty of Medicine, Medical University-Pleven, 5800 Pleven, Bulgaria.
Obstetrics Clinic, UMHAT "Saint Marina" Pleven, 5800 Pleven, Bulgaria.
J Clin Med. 2024 Feb 7;13(4):950. doi: 10.3390/jcm13040950.
: The ophthalmic Doppler is a reliable and impartial way to assess the severity of preeclampsia (PE). The study aimed to assess the potential utility of Doppler measurements of the maternal ophthalmic arteries during the weeks 19-23 of gestation, both independently and in combination with established biomarkers for PE. A prospective cohort study was conducted involving women who were recruited from a variety of standard appointments, including booking, scanning, and regular prenatal visits. A total of 200 women that were divided into high-risk and low-risk groups for developing PE were involved during the period between April 2023 and November 2023. The ophthalmic ratio had significantly higher values in high-risk patients than in low-risk women ( = 0.000). There was a significant relationship between PSV2/PSV1 and gestational age at birth in women with PE compared to the ones who did not develop PE. An ophthalmic artery Doppler can play a crucial role in the early detection of PE, allowing for timely intervention and management. Incorporating the ophthalmic artery Doppler as a screening tool for PE in Bulgaria has the potential to improve early detection, risk stratification, and overall maternal and fetal health outcomes.
眼科多普勒是评估子痫前期(PE)严重程度的一种可靠且公正的方法。该研究旨在评估妊娠19至23周期间母体眼动脉多普勒测量的潜在效用,包括单独使用以及与已确立的PE生物标志物联合使用。进行了一项前瞻性队列研究,研究对象为从各种标准预约(包括建档、超声检查和定期产前检查)中招募的女性。在2023年4月至2023年11月期间,共纳入了200名分为PE高危组和低危组的女性。高危患者的眼动脉比值显著高于低危女性(P = 0.000)。与未发生PE的女性相比,发生PE的女性中PSV2/PSV1与出生时的孕周之间存在显著关系。眼动脉多普勒在PE的早期检测中可发挥关键作用,并能及时进行干预和管理。在保加利亚,将眼动脉多普勒作为PE的筛查工具有可能改善早期检测、风险分层以及母婴总体健康结局。