丙硫异烟胺和氨苯砜治疗麻风病的临床研究
Prothionamide and dapsone therapy in leprosy--a clinical study.
作者信息
Kundu S K, Hazra S K, Chaudhury S K, Chatterjee B
出版信息
Indian J Lepr. 1985 Jan-Mar;57(1):90-6.
PMID:3839829
Abstract
Combined therapy with prothionamide and dapsone was instituted in fifteen active untreated lepromatous leprosy cases for a period of 18 months. Clinical improvement was good with attainment of zero morphological index in about 66% cases. Bacteriological improvement was rather unsatisfactory as one case only reached zero level. Side effects were observed in few cases necessitating withdrawal of combined therapy and patients' prothionamide compliance was rather unimpressive.
摘要
对15例未经治疗的活动性瘤型麻风病例采用丙硫异烟胺和氨苯砜联合治疗，为期18个月。临床改善良好，约66%的病例达到形态学指数为零。细菌学改善相当不令人满意，因为只有1例达到零水平。少数病例观察到副作用，需要停用联合治疗，患者对丙硫异烟胺的依从性相当不理想。
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