Pérez Martín Jaime Jesús, Zornoza Moreno Matilde, Tornel Miñarro Francisca Isabel, Gómez Moreno María Cruz, Valcárcel Gómez María Del Carmen, Pérez Martínez Marta
Affiliation Vaccination Program, Prevention and Health Protection Service, Public Health and Addictions Directorate General, Region of Murcia Ministry of Health, 30008 Murcia, Spain.
Vaccines (Basel). 2024 Feb 13;12(2):192. doi: 10.3390/vaccines12020192.
The high burden of influenza in children has driven numerous countries towards universal vaccination of healthy children from 6 to 59 months of age. The Region of Murcia was one of the pioneer Spanish regions to conduct a universal vaccination campaign and to use live-attenuated intranasal vaccine (LAIV) if age appropriate. This study aims to evaluate the parents' likeliness to vaccinate their children and to compare the profile of vaccinating/non-vaccinating parents. This study was designed as a prospective, real-world, survey-based data collection in the 2022-2023 season campaign. This study's sample was selected from those children whose information was available in the local Public Health System databases PERSAN and VACUSAN. Children received LAIV or intramuscular vaccine (IIV) depending on their age as per standard practice. The parent self-vaccination/intention to vaccinate themselves in this campaign (OR = 4.75), the compliance with the official vaccination schedule (OR = 3.41), and the prescription of antibiotics more than twice in the previous year (OR = 2.24) were strongly associated with children's vaccination. Overall, vaccinating parents were very satisfied with the vaccine (IIV: 67.5% vs. LAIV: 68.8%, = 0.320), and most parents would rather have their children vaccinated with LAIV for the next campaign (43.0%). The main reasons for vaccinating were to protect the child (LAIV: 85.9% vs. IIV: 89.4%), and the predominant reasons for not vaccinating were a lack of healthcare professional recommendation (30.9%), and lack of information about the vaccination campaign (21.5%) and the vaccine itself (21.0%). The clinical context of parents and children was determinant in decision making, which was also influenced by the presence or absence of recommendation by healthcare professionals. Parents were generally very satisfied with the vaccine and showed their preference towards LAIV for future campaigns.
儿童流感的高负担促使许多国家对6至59个月大的健康儿童进行普遍接种。穆尔西亚地区是西班牙率先开展普遍接种运动并在年龄适当时使用减毒活流感鼻喷雾剂疫苗（LAIV）的地区之一。本研究旨在评估父母为其子女接种疫苗的可能性，并比较接种/未接种疫苗父母的特征。本研究设计为在2022 - 2023年季节接种运动中基于调查的前瞻性真实世界数据收集。本研究的样本选自当地公共卫生系统数据库PERSAN和VACUSAN中可获取信息的儿童。根据标准做法，儿童根据年龄接种LAIV或肌肉注射疫苗（IIV）。父母在本次接种运动中的自我接种/接种意愿（比值比 = 4.75）、对官方接种计划的依从性（比值比 = 3.41）以及前一年抗生素处方超过两次（比值比 = 2.24）与儿童接种疫苗密切相关。总体而言，接种疫苗的父母对疫苗非常满意（IIV：67.5% 对 LAIV：68.8%，P = 0.320），并且大多数父母希望他们的孩子在下一次接种运动中接种LAIV（43.0%）。接种疫苗的主要原因是保护孩子（LAIV：85.9% 对 IIV：89.4%），未接种疫苗的主要原因是缺乏医疗保健专业人员的建议（30.9%）、缺乏关于接种运动的信息（21.5%）以及缺乏关于疫苗本身的信息（21.0%）。父母和孩子的临床情况在决策中起决定性作用，这也受到医疗保健专业人员是否给出建议的影响。父母总体上对疫苗非常满意，并表示他们倾向于在未来的接种运动中使用LAIV。
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