Wu Tong, Zhou Luolin, Liao Xinru, He Yuewen, Xu Ronglin, Luo Daihong
First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Beijing University of Chinese Medicine Shenzhen Hospital (Longgang), Shenzhen, China.
Complement Ther Med. 2024 May;81:103029. doi: 10.1016/j.ctim.2024.103029. Epub 2024 Feb 23.
Hypertension is a prevalent condition with significant impacts on human health. Chinese herbal foot bath, a traditional Chinese medicine treatment, is believed to help manage hypertension.
This systematic review aims to assess the efficacy of combining Chinese herbal foot bath with conventional treatment for hypertension.
A thorough search across eight databases was conducted to identify relevant studies on Chinese herbal foot bath for hypertension. Randomized controlled trials examining the benefits and risks of using Chinese herbal foot bath combined with conventional treatment for hypertension were included. Blood pressure changes before and after the Chinese herbal foot bath were assessed, and outcomes were analyzed using Review Manager 5.3 software. The certainty of evidence was evaluated using the GRADE tool.
Compared to conventional treatment, Chinese herbal foot bath combined with conventional treatment demonstrated greater effectiveness in reducing systolic blood pressure (MD 6.69, 95% CI: 5.86 to 7.53, p < 0.00001) and diastolic blood pressure (MD 5.83, 95% CI: 5.23 to 6.43, p < 0.00001), which reported fewer adverse effects.These studies commonly present issues such as inadequate randomization, lack of blinding, and absence of independent testing for the purity or potency of herbs.
The meta-analysis suggests that Chinese herbal foot bath combined with conventional treatment may effectively manage hypertension, with few adverse effects. However, high-quality clinical trials are still needed to confirm these findings due to methodological weaknesses in randomization, blinding, long-term follow-up, and independent testing for the purity and potency of herbs.
高血压是一种普遍存在的疾病，对人类健康有重大影响。中药足浴作为一种中医疗法，被认为有助于控制高血压。
本系统评价旨在评估中药足浴联合传统治疗对高血压的疗效。
全面检索了8个数据库，以确定有关中药足浴治疗高血压的相关研究。纳入了考察中药足浴联合传统治疗高血压的益处和风险的随机对照试验。评估了中药足浴前后的血压变化，并使用Review Manager 5.3软件分析结果。使用GRADE工具评估证据的确定性。
与传统治疗相比，中药足浴联合传统治疗在降低收缩压（MD 6.69，95%CI：5.86至7.53，p<0.00001）和舒张压（MD 5.83，95%CI：5.23至6.43，p<0.00001）方面显示出更大的效果，且不良反应较少。这些研究普遍存在随机化不足、缺乏盲法以及未对草药的纯度或效力进行独立检测等问题。
荟萃分析表明，中药足浴联合传统治疗可能有效控制高血压，且不良反应较少。然而，由于随机化、盲法、长期随访以及草药纯度和效力独立检测方面的方法学缺陷，仍需要高质量的临床试验来证实这些发现。
