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腹腔注射δ-睡眠诱导肽(DSIP)后猫的睡眠时间减少。

Reduced sleep in cats after intraperitoneal injection of delta-sleep-inducing peptide (DSIP).

作者信息

Sommerfelt L

出版信息

Neurosci Lett. 1985 Jul 4;58(1):73-7. doi: 10.1016/0304-3940(85)90331-3.

Abstract

The effect of intraperitoneally injected delta-sleep-inducing peptide (DSIP) on sleep-wakefulness in cats was studied using EEG, EMG and EOG recording for 10 h following 30 nmol/kg DSIP or control saline i.p. injections. DSIP reduced the amount of sleep, specifically light slow-wave sleep and REM sleep, and REM sleep latency was increased. The results suggest that in cats with redundancy sleep DSIP increases wakefulness at the cost of light slow-wave sleep, and in addition it has a specific REM-reducing effect.

摘要

通过脑电图(EEG)、肌电图(EMG)和眼电图(EOG)记录,研究了腹腔注射δ-睡眠诱导肽(DSIP)对猫睡眠-觉醒的影响,在腹腔注射30 nmol/kg DSIP或对照生理盐水后记录10小时。DSIP减少了睡眠时间,特别是浅慢波睡眠和快速眼动睡眠,并且快速眼动睡眠潜伏期增加。结果表明,在有多余睡眠的猫中,DSIP以浅慢波睡眠为代价增加觉醒,此外它还有特定的减少快速眼动睡眠的作用。

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