Albada J, Hordijk G J, van Unnik J A, Dekker A W
Cancer. 1985 Dec 15;56(12):2911-3. doi: 10.1002/1097-0142(19851215)56:12<2911::aid-cncr2820561231>3.0.co;2-v.
The authors retrospectively analyzed 103 patients to investigate the value of examination of Waldeyer's ring with biopsies as a staging procedure in patients with non-Hodgkin's lymphoma. Twenty-three patients had clinical involvement of Waldeyer's ring. In 55 of 80 remaining patients, this staging procedure was performed but positive biopsy specimens were found only in patients with advanced disease. No correlation was found between positive biopsy specimens and the histologic subtype. No positive biopsy specimens of Waldeyer's ring were obtained in patients with cervical lymphadenopathy without clinical involvement of the nasopharynx and in patients with localized lymphoma of the gastrointestinal tract. Blind biopsies of Waldeyer's ring as a staging procedure proved to be of no value in the patients. The results of therapy in 23 patients with involvement of Waldeyer's ring were good. Unfavorable histologic subtypes (intermediate or high-grade malignancy) were predominant (91%). Eighteen of 22 patients (82%) achieved complete remission, with a relapse-free survival rate at 60 months of 95%. For the whole group of patients, the actuarial survival rate at 72 months was 71%.
作者回顾性分析了103例患者，以研究对Waldeyer环进行活检检查作为非霍奇金淋巴瘤患者分期程序的价值。23例患者临床上有Waldeyer环受累。在其余80例患者中的55例中，进行了该分期程序，但仅在晚期疾病患者中发现活检标本呈阳性。活检标本阳性与组织学亚型之间未发现相关性。在无鼻咽部临床受累的颈部淋巴结病患者和胃肠道局限性淋巴瘤患者中，未获得Waldeyer环的阳性活检标本。对Waldeyer环进行盲目活检作为分期程序对患者无价值。23例Waldeyer环受累患者的治疗效果良好。不良组织学亚型（中度或高度恶性）占主导（91%）。22例患者中的18例（82%）实现完全缓解，60个月时无复发生存率为95%。对于整个患者组，72个月时的精算生存率为71%。
