Ahronovich Elan, Shen Jin-Hui, Vadakkan Tegy J, Prasad Ratna, Joos Karen M, Simaan Nabil
Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, USA.
Vanderbilt Eye Institute, Vanderbilt University 2311 Pierce Avenue Nashville, TN 37232, USA.
Biomed Opt Express. 2024 Jan 29;15(2):1150-1162. doi: 10.1364/BOE.505294. eCollection 2024 Feb 1.
Handheld optical coherence tomography (HH-OCT) is gaining popularity for diagnosing retinal diseases in neonates (e.g. retinopathy of prematurity). Diagnosis accuracy is degraded by hand tremor and patient motion when using commercially available handheld retinal OCT probes. This work presents a low-cost arm designed to address ergonomic challenges of holding a commercial OCT probe and alleviating hand tremor. Experiments with a phantom eye show enhanced geometric uniformity and volumetric accuracy when obtaining OCT scans with our device compared to handheld imaging approaches. An in-vivo porcine volumetric image was also obtained with the mechanical arm demonstrating clinical deployability.
手持式光学相干断层扫描（HH-OCT）在诊断新生儿视网膜疾病（如早产儿视网膜病变）方面越来越受欢迎。使用市售的手持式视网膜OCT探头时，手部震颤和患者移动会降低诊断准确性。这项工作提出了一种低成本的机械臂，旨在解决手持商用OCT探头时的人体工程学挑战，并减轻手部震颤。与手持式成像方法相比，使用我们的设备对模拟眼进行实验时，OCT扫描的几何均匀性和体积准确性得到了提高。使用该机械臂还获得了猪的体内体积图像，证明了其临床可部署性。
