Berdat Pascal A, Vogt Paul R, Schai Pascal A, Kurrer Michael O, Rüedi Christian, Brück Michael B, Exner G Ulrich
Heart Care Medical AG, Zurich, Switzerland.
Luzerner Kantonsspital Wolhusen, Wolhusen, Switzerland.
Case Rep Oncol. 2024 Feb 23;17(1):352-360. doi: 10.1159/000536350. eCollection 2024 Jan-Dec.
Rarely solitary sternum metastases are addressed by resection. Two additional cases are presented as they are interesting because of their long-term follow-up.
Case 1: A renal cell carcinoma was treated by transabdominal nephrectomy at age 64. Right iliac bone and sternum metastases were diagnosed 7 months later and treated by internal hemipelvectomy followed by sternum metastasectomy 6 weeks after the internal hemipelvectomy. At 12-year follow-up, the patient appears disease free. Case 2: Prostate cancer was treated by prostatectomy at age 67. A subsequent solitary sternum metastasis was resected 10 years later for persistent PSA-activity despite repeated radiotherapy. The patient remains asymptomatic for 3 years now.
Resection of sternum metastases may have curative potential and should be considered in tumours known to be rather resistant to chemo- and/or radiotherapy.
孤立性胸骨转移瘤很少通过手术切除来处理。现报告另外两例，因其长期随访结果有趣。
病例1：一名64岁的肾细胞癌患者接受了经腹肾切除术。7个月后诊断出右髂骨和胸骨转移，先行半骨盆切除术，6周后行胸骨转移瘤切除术。随访12年，患者无疾病迹象。病例2：一名67岁的前列腺癌患者接受了前列腺切除术。10年后，尽管反复放疗，但因前列腺特异性抗原（PSA）持续升高，对其孤立性胸骨转移瘤进行了切除。患者至今已无症状3年。
胸骨转移瘤切除术可能具有治愈潜力，对于已知对化疗和/或放疗耐药的肿瘤应考虑采用该方法。
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