Eroglu A, Karaoglanoglu N, Bilen H, Gursan N
Department of Thoracic Surgery, Ataturk University, Erzurum, Turkey.
Int J Clin Pract. 2006 Nov;60(11):1506-8. doi: 10.1111/j.1742-1241.2005.00637.x.
Primary and metastatic malignancies of the sternum are uncommon. Secondary lesions to the sternum occur more commonly in patients with lung and breast cancer, and only a few cases of sternal metastasis arising from a follicular thyroid carcinoma have been reported in the literature. Rarely, metastases to the sternum present in the guise of primary sternal tumours may be treated surgically with that diagnosis in mind. We describe a case of a sternal mass treated by radical surgery, which ultimately proved to be a solitary metastasis from a follicular carcinoma of the thyroid, appearing 13 years after total thyroidectomy and radioactive iodine therapy. Late metastatic thyroid carcinoma to the sternum should be kept in mind in the differential diagnosis of sternal lesions. For patients with thyroid carcinoma and sternal metastasis, we recommend surgical resection of the metastasis, not only as a curative or palliative measure but also to maximise the effect of subsequent radioiodine treatment.
胸骨原发性和转移性恶性肿瘤并不常见。胸骨继发性病变在肺癌和乳腺癌患者中更为常见，而文献中仅报道了少数几例由滤泡状甲状腺癌引起的胸骨转移病例。很少有以原发性胸骨肿瘤形式出现的胸骨转移瘤会在考虑该诊断的情况下接受手术治疗。我们描述了一例通过根治性手术治疗的胸骨肿块病例，最终证实其为甲状腺滤泡状癌的孤立转移瘤，发生在甲状腺全切除和放射性碘治疗13年后。在胸骨病变的鉴别诊断中应考虑到晚期甲状腺癌转移至胸骨的情况。对于患有甲状腺癌和胸骨转移的患者，我们建议手术切除转移瘤，这不仅是一种治愈性或姑息性措施，而且还能使后续放射性碘治疗的效果最大化。
