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瑞典法医精神病患者出院后药物治疗的中断情况。

Post-discharge pharmacological treatment discontinuation of forensic psychiatric patients in Sweden.

作者信息

Noland Ebba, Virtanen Suvi, Klötz Logan Fia, Chang Zheng, Strandh Mattias

机构信息

Department of Social Work, Umeå University, Umeå, Sweden.

Sundsvall Forensic Psychiatric Centre, Region Västernorrland, Sundsvall, Sweden.

出版信息

Front Psychiatry. 2024 Feb 9;15:1342722. doi: 10.3389/fpsyt.2024.1342722. eCollection 2024.

Abstract

INTRODUCTION

Most forensic psychiatric patients have chronic psychiatric disorders that require long-term pharmacological treatment even after discharge from care. However, the prevalence and correlates of post-discharge medication discontinuation in this patient group remain unclear.

OBJECTIVE

The aim of this study was to investigate the prevalence and correlates of post-discharge discontinuation of pharmacological treatment in forensic psychiatric patients in Sweden.

METHODS

Data on individuals discharged from forensic psychiatric care between 2009 and 2018 ( = 1,142) with ongoing pharmacological treatment at the time of discharge ( = 856) were identified from the Swedish National Forensic Psychiatric Register. Cox regression models were used to estimate the association between patient characteristics and medication discontinuation.

RESULTS

Of the 856 individuals with pharmacological treatment at discharge, 488 (57%) discontinued treatment within 2 years of discharge. Factors associated with an increased risk of treatment discontinuation varied between different types of psychotropic medications: the most important correlate was comorbidity between psychosis and personality disorder. Higher age at discharge, longer length of stay, having a history of several psychiatric care episodes, having a trustee, having a limited guardian, and a residing in a supported living accommodation at the time of discharge were associated with a decreased rate of medication discontinuation. This applied for antipsychotics, antidepressants, antiepileptics, and any psychotropic medication, but not for psychostimulants or drugs used in addictive disorders.

CONCLUSION

For many former forensic psychiatric patients, there are situational factors associated with medication discontinuation. This insight holds significance for professionals who are involved in pre-discharge planning within forensic psychiatric care and those who interact with this cohort of former patients post-discharge.

摘要

引言

大多数法医精神病患者患有慢性精神疾病,即使在出院后也需要长期药物治疗。然而,该患者群体出院后停药的患病率及其相关因素仍不清楚。

目的

本研究旨在调查瑞典法医精神病患者出院后药物治疗停药的患病率及其相关因素。

方法

从瑞典国家法医精神病登记册中识别出2009年至2018年间从法医精神病护理机构出院的个体数据(n = 1,142),这些个体在出院时正在接受药物治疗(n = 856)。使用Cox回归模型估计患者特征与停药之间的关联。

结果

在856名出院时接受药物治疗的个体中,488名(57%)在出院后2年内停药。与停药风险增加相关的因素因不同类型的精神药物而异:最重要的相关因素是精神病与人格障碍的共病。出院时年龄较大、住院时间较长、有多次精神病护理经历、有受托人、有有限监护人以及出院时居住在支持性居住场所与停药率降低相关。这适用于抗精神病药、抗抑郁药、抗癫痫药和任何精神药物,但不适用于精神兴奋剂或成瘾性疾病中使用的药物。

结论

对于许多以前的法医精神病患者来说,存在与停药相关的情境因素。这一见解对于参与法医精神病护理出院前规划的专业人员以及出院后与这一群体的前患者互动的人员具有重要意义。

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