Hamad Heba R, Alamin Shoroq, Alotaibi Moteb A
College of Medicine, Sulaiman Al Rajhi University, Al-Bukayriyah, SAU.
Medicine, Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, SAU.
Cureus. 2024 Jan 24;16(1):e52892. doi: 10.7759/cureus.52892. eCollection 2024 Jan.
Lichen planopilaris (LPP) is an uncommon inflammatory scalp condition. Its typical clinical presentation includes scaly, erythematous plaques resulting in irreversible alopecia. In this study, we report a female in her late 30s with hypothyroidism and Crohn's disease. She presented with gradual, localized hair loss that had been ongoing for the past four months. A thorough physical examination, and complemented by dermoscopic evaluation, confirmed the diagnosis of LPP. Individuals who have an autoimmune disease (AID) have a heightened propensity to develop additional AID. The coexistence of three or more AIDs falls under the definition of multiple autoimmune syndrome (MAS). This is the first case, to the best of our knowledge, of LPP being associated with MAS.
扁平苔藓性毛发角化病（LPP）是一种罕见的头皮炎症性疾病。其典型临床表现包括鳞屑性红斑斑块，可导致不可逆的脱发。在本研究中，我们报告了一名30多岁晚期的女性，患有甲状腺功能减退症和克罗恩病。她出现渐进性局部脱发，已持续四个月。全面的体格检查，并辅以皮肤镜评估，确诊为LPP。患有自身免疫性疾病（AID）的个体发生其他AID的倾向增加。三种或更多种AID并存属于多发性自身免疫综合征（MAS）的定义范畴。据我们所知，这是首例LPP与MAS相关的病例。
