Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Pharmaceutical Biotechnology, Shiraz University of Medical Sciences, Shiraz, Iran.
J Cosmet Dermatol. 2024 Jun;23(6):2156-2169. doi: 10.1111/jocd.16255. Epub 2024 Feb 26.
Acne is a common skin issue that typically occurs during adolescence. It causes long-lasting redness and swelling in the skin. An alternative approach to treating acne could involve using a cosmetic facial mask containing herbal ingredients such as Curcumin and Rosa Damascena extract for its antibacterial properties.
This study aims to create and try out a peel-off mask gel made from Curcumin and R. Damascena extract. This gel is intended to have the ability to kill bacteria such as Staphylococcus aureus, Escherichia coli, and Propionibacterium acnes and remove dead cells from the skin surface.
The peel-off mask was made using polyvinyl alcohol (PVA) in 8% and 10% as solidifier. The evaluation of peel-off masks comprises the examination of physiochemical and mechanical aspects. Furthermore, their longevity, effectiveness, and antibacterial properties are also considered.
The white color, pleasant smell, and soft texture were the defining features of the peel-off gel mask. The changes in PVA affect the pH level, thickness, and how quickly the peel-off mask dries. The stability test found that the peel-off mask had no significant physical changes when exposed to freezing and thawing. However, there were some differences in color and separation when using the real-time method. A prepared peel-off mask containing 10% PVA and curcumin works best against P. acne. The amount of PVA in the formula affected the physical and chemical qualities, but it did not impact on the antibacterial abilities of the peel-off mask gel. The best formula that gives the best results uses 10% PVA + curcumin.
Using the Curcumin and R. Damascena extract in the creation of the peel-off mask gel ensures its efficacy and safety for skin application.
痤疮是一种常见的皮肤问题,通常发生在青春期。它会导致皮肤长时间红肿和肿胀。治疗痤疮的另一种方法可能涉及使用含有草药成分(如姜黄素和大马士革玫瑰提取物)的美容面膜,因为其具有抗菌特性。
本研究旨在开发并试用一种由姜黄素和大马士革玫瑰提取物制成的撕拉式面膜凝胶。该凝胶旨在具有杀死金黄色葡萄球菌、大肠杆菌和痤疮丙酸杆菌等细菌的能力,并去除皮肤表面的死细胞。
使用 8%和 10%的聚乙烯醇(PVA)作为固体剂来制作撕拉式面膜。对撕拉式面膜的评估包括对其理化和机械方面的检查。此外,还考虑了其保质期、有效性和抗菌性能。
撕拉式凝胶面膜具有白色、气味宜人、质地柔软等特点。PVA 的变化会影响 pH 值、厚度以及撕拉式面膜干燥的速度。稳定性测试发现,撕拉式面膜在经受冷冻和解冻时没有明显的物理变化。然而,在使用实时方法时,颜色和分离方面会存在一些差异。含有 10% PVA 和姜黄素的制备好的撕拉式面膜对痤疮丙酸杆菌的抑制效果最好。配方中 PVA 的含量会影响物理和化学性质,但不会影响撕拉式面膜凝胶的抗菌能力。效果最佳的最佳配方是使用 10% PVA+姜黄素。
在撕拉式面膜凝胶的制作中使用姜黄素和大马士革玫瑰提取物可确保其对皮肤应用的功效和安全性。