T4噬菌体组装与运作的模拟
A simulation of T4 bacteriophage assembly and operation.
作者信息
Thompson R L, Goel N S
出版信息
Biosystems. 1985;18(1):23-45. doi: 10.1016/0303-2647(85)90058-9.
PMID:3840704
Abstract
A model is presented for the self-assembly and operation of a bacteriophage comparable with the T4 bacteriophage that infects Escherichia coli. The model treats protein molecules as simple units obeying the principle free energy minimization, and exhibiting the properties of quasi-equivalence and conformational switching. A computer program incorporating the model has been developed. The results of simulation using this program are presented.
摘要
本文提出了一种与感染大肠杆菌的T4噬菌体类似的噬菌体自组装和运行模型。该模型将蛋白质分子视为遵循自由能最小化原则的简单单元，并展现出准等价和构象转换的特性。已开发出一个包含该模型的计算机程序，并给出了使用此程序的模拟结果。
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