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Ultra-High-Risk Gestational Choriocarcinoma of the Ovary Associated with Ectopic Pregnancy.卵巢超高危妊娠绒癌合并宫外孕。
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Diagnostics (Basel). 2022 Feb 22;12(3):560. doi: 10.3390/diagnostics12030560.
3
Primary Ovarian Choriocarcinoma: Rare Entity.原发性卵巢绒毛膜癌:罕见实体。
Case Rep Obstet Gynecol. 2021 Sep 24;2021:4545375. doi: 10.1155/2021/4545375. eCollection 2021.
4
Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non-gestational choriocarcinomas and malignant mixed germ cell tumors.妇科疾病影像学(二十二):卵巢胚胎性癌、非妊娠绒毛膜癌和恶性混合生殖细胞肿瘤的临床和超声特征。
Ultrasound Obstet Gynecol. 2021 Jun;57(6):987-994. doi: 10.1002/uog.23529.
5
Relative Effects of Age, Race, and Stage on Mortality in Gestational Choriocarcinoma.年龄、种族和分期对妊娠绒癌死亡率的相对影响。
Int J Gynecol Cancer. 2018 Feb;28(2):338-345. doi: 10.1097/IGC.0000000000001156.
6
Primary ovarian choriocarcinoma mimicking ectopic pregnancy.酷似异位妊娠的原发性卵巢绒毛膜癌。
Obstet Gynecol Sci. 2014 Jul;57(4):330-3. doi: 10.5468/ogs.2014.57.4.330. Epub 2014 Jul 15.
7
Pure choriocarcinoma of the ovary: a case report.单纯卵巢绒癌:一例报告。
J Gynecol Oncol. 2011 Jun 30;22(2):135-9. doi: 10.3802/jgo.2011.22.2.135.
8
Pure ovarian choriocarcinoma: report of two cases.纯卵巢绒毛膜癌:两例报告。
J Res Med Sci. 2009 Sep;14(5):327-30.
9
Elevated HCG outside of pregnancy--diagnostic considerations and laboratory evaluation.非妊娠状态下的人绒毛膜促性腺激素升高——诊断考量与实验室评估
Obstet Gynecol Surv. 2007 Oct;62(10):669-74; quiz 691. doi: 10.1097/01.ogx.0000281556.13788.61.
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Elevated serum beta-human chorionic gonadotropin in nonpregnant conditions.非妊娠状态下血清β-人绒毛膜促性腺激素升高。
Obstet Gynecol Surv. 2007 Oct;62(10):675-9; quiz 691. doi: 10.1097/01.ogx.0000281557.04956.61.

卵巢绒毛膜癌的罕见病例:超声评估

Rare occurrence of ovarian choriocarcinoma: ultrasound evaluation.

作者信息

Youssef Ashraf Talaat

机构信息

Radiology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt.

出版信息

J Ultrasound. 2025 Mar;28(1):213-216. doi: 10.1007/s40477-023-00868-3. Epub 2024 Feb 26.

DOI:10.1007/s40477-023-00868-3
PMID:38409507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11947387/
Abstract

Choriocarcinoma of the ovary is a rare, highly malignant tumor showing malignant trophoblastic cells and produces human chorionic gonadotropins. It can be classified as gestational and non-gestational choriocarcinoma. Non-gestational choriocarcinoma is extremely rare. Treatment is Methotrexate-based chemotherapy for the gestational type. This case study is a rare case of ovarian choriocarcinoma managed by surgical resection, followed by methotrexate-based chemotherapy, and aimed to evaluate the ultrasound characteristics of ovarian choriocarcinoma and how to arrive at the diagnosis. In cases with an elevated serum beta-human chorionic gonadotropin (beta hCG), the finding of a highly vascularized adnexal mass on ultrasound evaluation should be underlined as a clue for suspecting choriocarcinoma, particularly if the female was young with no marriage history or history of sexual intercourse and also to be highly considered in married females with history of repeated abortions, molar pregnancy or uterine choriocarcinoma.

摘要

卵巢绒毛膜癌是一种罕见的高度恶性肿瘤,由恶性滋养层细胞构成,并产生人绒毛膜促性腺激素。它可分为妊娠性和非妊娠性绒毛膜癌。非妊娠性绒毛膜癌极为罕见。妊娠型绒毛膜癌的治疗是以甲氨蝶呤为基础的化疗。本病例研究是一例通过手术切除,随后进行以甲氨蝶呤为基础的化疗来治疗的罕见卵巢绒毛膜癌病例,旨在评估卵巢绒毛膜癌的超声特征以及如何做出诊断。在血清β-人绒毛膜促性腺激素(β-hCG)升高的病例中,超声检查发现附件区有高度血管化的肿块应作为怀疑绒毛膜癌的线索予以重视,特别是当女性年轻且无婚史或无性交史时,对于有反复流产、葡萄胎妊娠或子宫绒毛膜癌病史的已婚女性也应高度怀疑。