Youssef Ashraf Talaat
Radiology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
J Ultrasound. 2025 Mar;28(1):213-216. doi: 10.1007/s40477-023-00868-3. Epub 2024 Feb 26.
Choriocarcinoma of the ovary is a rare, highly malignant tumor showing malignant trophoblastic cells and produces human chorionic gonadotropins. It can be classified as gestational and non-gestational choriocarcinoma. Non-gestational choriocarcinoma is extremely rare. Treatment is Methotrexate-based chemotherapy for the gestational type. This case study is a rare case of ovarian choriocarcinoma managed by surgical resection, followed by methotrexate-based chemotherapy, and aimed to evaluate the ultrasound characteristics of ovarian choriocarcinoma and how to arrive at the diagnosis. In cases with an elevated serum beta-human chorionic gonadotropin (beta hCG), the finding of a highly vascularized adnexal mass on ultrasound evaluation should be underlined as a clue for suspecting choriocarcinoma, particularly if the female was young with no marriage history or history of sexual intercourse and also to be highly considered in married females with history of repeated abortions, molar pregnancy or uterine choriocarcinoma.
卵巢绒毛膜癌是一种罕见的高度恶性肿瘤,由恶性滋养层细胞构成,并产生人绒毛膜促性腺激素。它可分为妊娠性和非妊娠性绒毛膜癌。非妊娠性绒毛膜癌极为罕见。妊娠型绒毛膜癌的治疗是以甲氨蝶呤为基础的化疗。本病例研究是一例通过手术切除,随后进行以甲氨蝶呤为基础的化疗来治疗的罕见卵巢绒毛膜癌病例,旨在评估卵巢绒毛膜癌的超声特征以及如何做出诊断。在血清β-人绒毛膜促性腺激素(β-hCG)升高的病例中,超声检查发现附件区有高度血管化的肿块应作为怀疑绒毛膜癌的线索予以重视,特别是当女性年轻且无婚史或无性交史时,对于有反复流产、葡萄胎妊娠或子宫绒毛膜癌病史的已婚女性也应高度怀疑。