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袖状胃切除术后反流:腹腔镜悬韧带固定术的安全性和有效性,单中心经验。

Reflux After Sleeve Gastrectomy: Safety and Effectiveness of Laparoscopic Ligamentum Teres Cardiopexy, a Single-Center Experience.

机构信息

Department of Bariatric Surgery, Orlando Regional Medical Center, Orlando Health, 89 W Copeland Dr, 1st Floor, Orlando, FL, USA.

Policlinica Itaipava, 12.235 Estarda Uniao e Industria, Petropolis, RJ, Brazil.

出版信息

Obes Surg. 2024 Apr;34(4):1232-1237. doi: 10.1007/s11695-024-07103-w. Epub 2024 Feb 26.

DOI:10.1007/s11695-024-07103-w
PMID:38409622
Abstract

BACKGROUND

Obesity is a well-known risk factor for gastroesophageal reflux disease (GERD). Even though symptoms may be mitigated or resolved with the weight loss caused by sleeve gastrectomy (SG), it may be associated with higher incidences of postoperative GERD. Ligamentum teres cardiopexy (LTC) is an alternative to Roux-en-Y gastric bypass, the gold standard treatment for GERD.

METHODS

This study was a retrospective single-center chart review, all patients in this cohort underwent LTC to treat refractory GERD at our institution. The option for LTC was presented after patients' refusal to undergo RYGB conversion. We collected baseline characteristics, standard demographics, pre-operative tests and imaging, and SG information, as well as intraoperative and perioperative data regarding LTC, and postoperative complications.

RESULTS

Our cohort included 29 patients; most were Caucasian (44.8%) females (86.2%). The mean weight and BMI before LTC were 216.5 ± 39.3 lb and 36.1 ± 5.4 kg/m, respectively. Mean total body-weight loss (TBWL) at 12 and 24 months were 28.7% ± 9.5% and 28.4% ± 12.4%, respectively. The mean interval between the index bariatric surgery and LTC was 59.9 ± 34.9 months, mean operative time was 67 ± 18.2 min, and median length of stay (LOS) was 1 day (IQR = 1-2 days). Twelve patients (57.1%) were able to discontinue antisecretory medications, while 9 (42.9%) still required them to remain asymptomatic. Mortality and reoperation rates were 0% and the incidence of complication was 19.4% (n = 6).

CONCLUSIONS

LTC is a safe and effective surgical alternative to treat refractory GERD symptoms after SG.

摘要

背景

肥胖是胃食管反流病(GERD)的已知危险因素。尽管袖状胃切除术(SG)引起的体重减轻可能会减轻或解决症状,但它可能与术后 GERD 的发生率较高有关。膈肌心包固定术(LTC)是治疗 GERD 的金标准治疗方法 Roux-en-Y 胃旁路术的替代方法。

方法

本研究是一项回顾性单中心图表回顾研究,本队列中的所有患者在我院均接受 LTC 治疗难治性 GERD。在患者拒绝进行 RYGB 转换后,提出了进行 LTC 的选择。我们收集了基线特征、标准人口统计学、术前检查和影像学以及 SG 信息,以及 LTC 的术中及围手术期数据和术后并发症。

结果

我们的队列包括 29 名患者;大多数是白人(44.8%)女性(86.2%)。LTC 前的平均体重和 BMI 分别为 216.5 ± 39.3 磅和 36.1 ± 5.4 kg/m。12 个月和 24 个月时的平均总体体重减轻(TBWL)分别为 28.7%±9.5%和 28.4%±12.4%。指数减肥手术后与 LTC 之间的平均间隔时间为 59.9 ± 34.9 个月,平均手术时间为 67 ± 18.2 分钟,中位住院时间(LOS)为 1 天(IQR = 1-2 天)。12 名患者(57.1%)能够停止抗分泌药物,而 9 名患者(42.9%)仍需要它们来保持无症状。死亡率和再手术率均为 0%,并发症发生率为 19.4%(n = 6)。

结论

LTC 是治疗 SG 后难治性 GERD 症状的安全有效的手术替代方法。

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本文引用的文献

1
Long-Term Outcomes of Sleeve Gastrectomy: Weight Recurrence and Surgical Non-responders.袖状胃切除术的长期结果:体重复发与手术无反应者。
Obes Surg. 2023 Oct;33(10):3028-3034. doi: 10.1007/s11695-023-06730-z. Epub 2023 Jul 18.
2
Ligamentum teres cardiopexy for post vertical sleeve gastrectomy gastroesophageal reflux.用于治疗垂直袖状胃切除术后胃食管反流的圆韧带动脉心脏固定术。
Surg Endosc. 2023 Sep;37(9):7247-7253. doi: 10.1007/s00464-023-10239-y. Epub 2023 Jul 5.
3
Ligamentum Teres Cardiopexy Might Not Prevent Gastro-esophageal Reflux After Laparoscopic Sleeve Gastrectomy: Case Series.
腹腔镜袖状胃切除术治疗后,圆韧带动脉固定术可能无法预防胃食管反流:病例系列。
Obes Surg. 2023 Mar;33(3):965-968. doi: 10.1007/s11695-022-06413-1. Epub 2022 Dec 31.
4
Gastroesophageal Reflux Disease.胃食管反流病
N Engl J Med. 2022 Sep 29;387(13):1207-1216. doi: 10.1056/NEJMcp2114026.
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Ten year comparative analysis of sleeve gastrectomy, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch in patients with BMI ≥ 50 kg/m.对 BMI≥50kg/m²患者行袖状胃切除术、Roux-en-Y 胃旁路术和胆胰分流十二指肠转位术的 10 年对比分析。
Surg Endosc. 2022 Jul;36(7):4946-4955. doi: 10.1007/s00464-021-08850-y. Epub 2021 Nov 3.
6
Laparoscopic Ligamentum Teres cardiopexy to the rescue; an old procedure with a new use in managing reflux after sleeve gastrectomy.腹腔镜下圆韧带心包固定术挽救术;在袖状胃切除术后处理反流中老方法新用途。
Am J Surg. 2021 Mar;221(3):602-605. doi: 10.1016/j.amjsurg.2020.12.036. Epub 2020 Dec 25.
7
The New Interest of Bariatric Surgeons in the Old Ligamentum Teres Hepatis.减重外科医生对陈旧性肝圆韧带的新兴趣。
Obes Surg. 2020 Nov;30(11):4592-4598. doi: 10.1007/s11695-020-04918-1. Epub 2020 Aug 17.
8
Barrett's esophagus after sleeve gastrectomy: a systematic review and meta-analysis.袖状胃切除术后 Barrett 食管:系统评价和荟萃分析。
Gastrointest Endosc. 2021 Feb;93(2):343-352.e2. doi: 10.1016/j.gie.2020.08.008. Epub 2020 Aug 14.
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Gastroesophageal reflux disease, obesity and laparoscopic sleeve gastrectomy: The burning questions.胃食管反流病、肥胖与腹腔镜袖状胃切除术:热点问题。
World J Gastroenterol. 2019 Sep 7;25(33):4805-4813. doi: 10.3748/wjg.v25.i33.4805.
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Dig Liver Dis. 2019 Oct;51(10):1375-1379. doi: 10.1016/j.dld.2019.04.010. Epub 2019 May 7.