Marchevsky A M, Gil J, Caccamo D
Arch Pathol Lab Med. 1985 Dec;109(12):1102-5.
A morphometric study of 11 pleural malignant mesotheliomas and 11 pleural reactive mesothelial proliferations is reported. Pleural biopsy specimens of these lesions were studied with a new system of video-based computerized interactive morphometry that allows the comparison of real-time images of nuclear profiles with computer-generated graphic standards for the purpose of estimating their diameters. Malignant mesotheliomas had nuclear profile diameters (NPDs) ranging from 4 to 14 micron and a mean NPD of 9.6 +/- 0.5 micron. Reactive mesothelial proliferations had NPDs ranging from 4 to 12 micron, but exhibited a significantly smaller mean NPD of 6.4 +/- 0.2 micron. The potential technical advantages of computerized interactive morphometry over other morphometric methods are discussed.
报告了一项对11例胸膜恶性间皮瘤和11例胸膜反应性间皮增生的形态计量学研究。使用基于视频的计算机交互式形态计量学新系统对这些病变的胸膜活检标本进行了研究，该系统能够将核轮廓的实时图像与计算机生成的图形标准进行比较，以估计其直径。恶性间皮瘤的核轮廓直径（NPDs）范围为4至14微米，平均NPD为9.6±0.5微米。反应性间皮增生的NPDs范围为4至12微米，但平均NPD明显较小，为6.4±0.2微米。讨论了计算机交互式形态计量学相对于其他形态计量学方法的潜在技术优势。
