Fowler J F, Callen J P, Hodge S J, Verdi G
J Am Acad Dermatol. 1985 Oct;13(4):645-9. doi: 10.1016/s0190-9622(85)70209-5.
A 22-year-old man presented with a progressive cutaneous eruption consisting of reddish-yellow papules and plaques on his face, which was histopathologically characteristic of a non-X histiocytosis. No systemic involvement was present. Monoclonal antibody staining of the tissue infiltrate was strongly positive for only OKT6. On electron microscopy, Langerhans (Birbeck) granules were not found. Four years of conservative treatment was unsuccessful. Spontaneous involution did not occur. Dermabrasion not only produced excellent cosmetic results, but on rebiopsy the histiocytic infiltrate was absent. There has been no recurrence in treated areas after 18 months.
一名22岁男性患者，面部出现进行性皮肤疹，表现为红黄丘疹和斑块，组织病理学特征为非X组织细胞增生症。无全身受累情况。组织浸润的单克隆抗体染色仅对OKT6呈强阳性。电子显微镜检查未发现朗格汉斯（Birbeck）颗粒。四年的保守治疗未成功。皮疹未自发消退。皮肤磨削术不仅取得了极佳的美容效果，而且再次活检时组织细胞浸润消失。18个月后治疗部位未复发。
