Palladium-Catalyzed Electrochemical Iodination of 1-Arylpyridine -Oxides.

The palladium-catalyzed C-H iodination of 1-arylpyridine -oxides proceeded under electrochemical oxidation conditions using I as an iodine source. The reaction of isoquinoline -oxides possessing various - or -substituted aryl groups at the 1-position proceeded to give the corresponding iodination products. Electron-donating groups on the aryl group facilitated the reaction to give relatively high yields of the product. The reaction was also found to be applicable to 2-aryl-3-picoline -oxides.