Northern Finland Birth Cohorts, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland.
Finnish Institute of Occupational Health, Helsinki, Finland.
Menopause. 2024 Apr 1;31(4):275-281. doi: 10.1097/GME.0000000000002327. Epub 2024 Feb 26.
To study the association between an advanced climacteric status at 46 years of age and current perceived work ability, the consequent 2-year accumulation of disability and unemployment days, and the 7-year incidence of disability pensions.
Study participants (n = 2,661) were recruited from the Northern Finland Birth Cohort 1966 study's 46-year follow-up in 2012. The participants' perceived work ability was investigated using the Work Ability Score (0-7 = poor vs 8-10 = good), along with potential covariates. Data concerning their consequent disability days, unemployment days, and disability pensions were collected from national registers. The association between their climacteric status at age 46 years, work ability, and working life participation was assessed using regression models.
The climacteric women were more often smokers and more often had a lower level of education. The odds ratio for poor perceived work ability was 1.41 (95% CI, 1.06-1.87), and the incidence rate ratios for disability and unemployment days during the 2-year follow-up were 1.09 (95% CI, 1.07-1.11) and 1.16 (95% CI, 1.14-1.18), respectively, for the climacteric women compared with the preclimacteric women in models adjusted for smoking and education. The 7-year hazard ratio for disability pensions was 1.72 (95% CI, 1.02-2.91) for the climacteric women.
An earlier menopausal transition is associated with poorer perceived work ability, and it predicts lower recorded work participation and a higher disability pension rate in subsequent years.
研究 46 岁时绝经状态提前与当前感知工作能力、随后 2 年残疾和失业天数的积累以及 7 年残疾养老金发生率之间的关系。
研究参与者(n=2661)来自 1966 年芬兰北部出生队列研究的 46 岁随访,于 2012 年进行。使用工作能力评分(0-7=差,8-10=好)评估参与者的感知工作能力,并结合潜在的协变量。从国家登记处收集他们随后的残疾天数、失业天数和残疾养老金的数据。使用回归模型评估他们 46 岁时的绝经期状况、工作能力和工作生活参与度之间的关系。
绝经期女性更可能是吸烟者,受教育程度也更低。感知工作能力差的优势比为 1.41(95%CI,1.06-1.87),在调整吸烟和教育因素的模型中,2 年随访期间残疾和失业天数的发病率比分别为 1.09(95%CI,1.07-1.11)和 1.16(95%CI,1.14-1.18)。调整后的 7 年残疾养老金发生率比为 1.72(95%CI,1.02-2.91)。
绝经状态提前与感知工作能力下降相关,并预测随后几年记录的工作参与度下降和残疾养老金率上升。