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主要腹部手术后并发症的医院费用:一项回顾性队列研究。

The hospital costs of complications following major abdominal surgery: a retrospective cohort study.

机构信息

Department of Anaesthesia, Austin Health, Heidelberg, Australia.

Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Australia.

出版信息

BMC Res Notes. 2024 Feb 27;17(1):59. doi: 10.1186/s13104-024-06720-z.

DOI:10.1186/s13104-024-06720-z
PMID:38414013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10900687/
Abstract

OBJECTIVE

Postoperative complications following major abdominal surgeries is a pressing concern for hospital care and health economics. Given the paucity of available cost data for patients undergoing major abdominal surgery, we evaluated the number and the severity of postoperative complications following major abdominal surgeries and calculated the costs borne by a single centre university hospital within an Australian healthcare system.

RESULTS

The overall incidence of postoperative complications for 1790 adult patients undergoing major abdominal surgeries (i.e., colonic, liver, small bowel resections and Whipple procedures) between January 2013 and June 2018 was 75.2%. Of these complications, 56.9% were minor (Clavien-Dindo (CVD) Grades I or II) and 15.5% were major (CVD Grades III or IV). As the severity of complications increased, median adjusted total hospital costs rose significantly, with a median (interquartile range [IQR]) of AUD 29,519.70 (IQR 21,828.80-40,527.90) in CVD Grade II versus AUD 50,702.40 (IQR 35,866.00-69,296.80) in CVD Grade III (p <.001). Further, developing one, two or three complications resulted in significantly increased hospital costs by AUD 2618.30 (13.3% increase), AUD 3605.50 (16.2% increase) and AUD 3173.00 (12.3% increase) (p <.0001), respectively, with an exponential spike in costs incurred by patients who developed more than three complications (AUD 23,719.70; 81.7% increase; p < 0001).

摘要

目的

腹部大手术后的术后并发症是医院护理和卫生经济学的一个紧迫问题。鉴于可用于接受腹部大手术的患者的成本数据有限,我们评估了 1790 例接受腹部大手术(即结肠、肝脏、小肠切除术和胰十二指肠切除术)的成年患者术后并发症的数量和严重程度,并计算了澳大利亚医疗体系中单家大学医院承担的成本。

结果

2013 年 1 月至 2018 年 6 月期间,1790 例成年患者接受腹部大手术后(即结肠、肝脏、小肠切除术和胰十二指肠切除术)的术后并发症总发生率为 75.2%。这些并发症中,56.9%为轻度(Clavien-Dindo (CVD) 分级 I 或 II),15.5%为重度(CVD 分级 III 或 IV)。随着并发症严重程度的增加,调整后的中位总住院费用显著升高,CVD 分级 II 的中位(四分位间距 [IQR])为 29519.70 澳元(IQR 21828.80-40527.90),CVD 分级 III 的为 50702.40 澳元(IQR 35866.00-69296.80)(p<.001)。此外,发生 1 种、2 种或 3 种并发症分别导致住院费用显著增加 2618.30 澳元(增加 13.3%)、3605.50 澳元(增加 16.2%)和 3173.00 澳元(增加 12.3%)(p<.0001),而发生 3 种以上并发症的患者的费用呈指数级增长(23719.70 澳元;增加 81.7%;p<.0001)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e99/10900687/7e61bfdaee82/13104_2024_6720_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e99/10900687/cb892e276122/13104_2024_6720_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e99/10900687/7e61bfdaee82/13104_2024_6720_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e99/10900687/cb892e276122/13104_2024_6720_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e99/10900687/7e61bfdaee82/13104_2024_6720_Figb_HTML.jpg

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C-reactive protein can predict anastomotic leak in colorectal surgery: a systematic review and meta-analysis.C-反应蛋白可预测结直肠手术吻合口漏:系统评价和荟萃分析。
Int J Colorectal Dis. 2021 Jun;36(6):1147-1162. doi: 10.1007/s00384-021-03854-5. Epub 2021 Feb 8.
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4
STROCSS 2019 Guideline: Strengthening the reporting of cohort studies in surgery.STROCSS 2019 指南:加强外科学队列研究报告。
Int J Surg. 2019 Dec;72:156-165. doi: 10.1016/j.ijsu.2019.11.002. Epub 2019 Nov 6.
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The outcomes and complications of pancreaticoduodenectomy (Whipple procedure): Cross sectional study.胰十二指肠切除术(Whipple 手术)的结果和并发症:横断面研究。
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