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本文引用的文献

1
Range and Frequency of Congenital Malformations Among Children With Cleft Lip and/or Palate.唇裂和/或腭裂患儿先天性畸形的范围和频率。
Cleft Palate Craniofac J. 2023 Aug;60(8):917-927. doi: 10.1177/10556656221089160. Epub 2022 Apr 5.
2
Comparison of Presurgical Anthropometric Measures of Right and Left Complete Unilateral Cleft Lip and/or Palate.单侧完全性唇裂和/或腭裂患者术前左右侧人体测量指标的比较。
Plast Reconstr Surg. 2022 Feb 1;149(2):248e-253e. doi: 10.1097/PRS.0000000000008769.
3
Isolated oral clefts and school grades: population-based cohort study from Norway.孤立性口腔裂和学校成绩:来自挪威的基于人群的队列研究。
BMJ Open. 2021 Oct 5;11(10):e046944. doi: 10.1136/bmjopen-2020-046944.
4
Final Posttreatment Occlusion in Patients With Unilateral Cleft Lip and Palate.单侧唇腭裂患者的最终术后闭塞
Cleft Palate Craniofac J. 2022 Jul;59(7):899-909. doi: 10.1177/10556656211028506. Epub 2021 Jul 8.
5
FAT4 identified as a potential modifier of orofacial cleft laterality.FAT4 被鉴定为口腔面裂偏侧性的一个潜在修饰因子。
Genet Epidemiol. 2021 Oct;45(7):721-735. doi: 10.1002/gepi.22420. Epub 2021 Jun 15.
6
Impact of Maternal Smoking on Nonsyndromic Clefts: Sex-Specific Associations With Side and Laterality.母亲吸烟对非综合征性唇腭裂的影响:与侧别和偏侧性的性别特异性关联。
Cleft Palate Craniofac J. 2021 Feb;58(2):181-188. doi: 10.1177/1055665620951099. Epub 2020 Aug 26.
7
Dental arch relationship outcomes for children with complete unilateral and complete bilateral cleft lip and palate in New Zealand.新西兰单侧完全性唇腭裂和双侧完全性唇腭裂患儿的牙弓关系结果。
Orthod Craniofac Res. 2019 Aug;22(3):147-152. doi: 10.1111/ocr.12300. Epub 2019 Mar 3.
8
Eighteen-Year Follow-Up of 160 Consecutive Individuals Born With Unilateral Cleft Lip or Cleft Lip and Alveolus Treated by the Oslo Cleft Lip and Palate Team.奥斯陆唇腭裂治疗团队对160例单侧唇裂或唇腭裂患者进行的18年随访
Cleft Palate Craniofac J. 2019 Aug;56(7):853-859. doi: 10.1177/1055665618820753. Epub 2019 Jan 27.
9
Reliability of a Categorical Scale (GOSLON) and a Continuous Scale (10-cm Visual Analog Scale) for Assessing Dental Arch Relationships Using Conventional Plaster and 3D Digital Orthodontic Study Models of Children With Complete Unilateral Cleft Lip and Palate.使用传统石膏模型和三维数字正畸研究模型,评估完全性单侧唇腭裂患儿牙弓关系的分类量表(GOSLON)和连续量表(10厘米视觉模拟量表)的可靠性。
Cleft Palate Craniofac J. 2019 Jan;56(1):84-89. doi: 10.1177/1055665618770054. Epub 2018 Apr 26.
10
Associations between laterality of orofacial clefts and medical and academic outcomes.口面部裂隙的偏侧性与医学及学术成果之间的关联。
Am J Med Genet A. 2018 Feb;176(2):267-276. doi: 10.1002/ajmg.a.38567. Epub 2017 Dec 12.

新西兰单侧唇腭裂患儿的腭裂侧别与牙弓关系结局

Cleft Laterality Dental Arch Relationship Outcomes for Children with Unilateral Cleft Lip and Palate in New Zealand.

作者信息

Fowler Peter V, Keall H, Kennedy D, Healey D, Thompson J M D

机构信息

Department of Oral Sciences, University of Otago Dental School, Dunedin, New Zealand.

Formerly Hospital Dental Department, Middlemore Hospital, Auckland, New Zealand.

出版信息

Cleft Palate Craniofac J. 2025 Jun;62(6):959-963. doi: 10.1177/10556656241234599. Epub 2024 Feb 27.

DOI:10.1177/10556656241234599
PMID:38414360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12120204/
Abstract

ObjectivesTo investigate cleft laterality dental arch relationship outcomes of children with non-syndromic complete unilateral cleft lip and palate (UCLP) in New Zealand.DesignA retrospective nationwide study.SettingsVirtual 3D orthodontic study models collected prior to undertaking secondary alveolar bone grafting.ParticipantsA total of 104 patients with UCLP (L = 80: R = 24).Outcome measuresFour calibrated assessors used the GOSLON Yardstick and 100 mm Visual Analogue Scale (VAS) to score the randomised models on 2 separate assessment sessions. Weighted Kappa were used to determine the intra/inter-rater reliability for the GOSLON and correlations for the VAS.ResultsIntra-rater reliability ranged from 0.57-0.88 (GOSLON) and 0.45-0.93 (VAS). Inter-rater reliability ranged from 0.62-0.86 (GOSLON) and 0.64-0.93 (VAS).GOSLON scores for the left UCLP were 31.2% for good/very good; 26.3% for fair; 42.5% for poor/very poor while the right UCLP scored 8.3% for good/very good; 37.5% for fair; 54.2% for poor/very poor. The mean VAS for left and right UCLP were 53.4 (sd 22.5) and 44.6 (sd 17.1) respectively. Neither the GOSLON nor VAS differences reached statistical significance (both  = .08).ConclusionsFrom a clinical perspective right UCLP had worse dental arch relationship outcomes, however, these differences failed to reach statistical significance. Further studies using larger sample sizes are required to determine if cleft laterality is an important consideration when investigating UCLP dental arch outcomes.

摘要

目的

调查新西兰非综合征性完全性单侧唇腭裂(UCLP)患儿的腭裂侧别与牙弓关系结果。

设计

一项全国性回顾性研究。

设置

在进行二次牙槽骨植骨术前收集的虚拟3D正畸研究模型。

参与者

共有104例UCLP患者(左侧=80例;右侧=24例)。

观察指标

4名经过校准的评估者使用戈斯隆标尺和100毫米视觉模拟量表(VAS)在2个独立的评估环节对随机模型进行评分。加权kappa系数用于确定戈斯隆评分的评分者内/评分者间信度以及VAS评分的相关性。

结果

评分者内信度范围为0.57 - 0.88(戈斯隆)和0.45 - 0.93(VAS)。评分者间信度范围为0.62 - 0.86(戈斯隆)和0.64 - 0.93(VAS)。

左侧UCLP的戈斯隆评分为:良好/非常好占31.2%;中等占26.3%;差/非常差占42.5%,而右侧UCLP评分为:良好/非常好占8.3%;中等占37.5%;差/非常差占54.2%。左侧和右侧UCLP的VAS平均评分分别为53.4(标准差22.5)和44.6(标准差17.1)。戈斯隆评分和VAS评分的差异均未达到统计学显著性(均P = 0.08)。

结论

从临床角度看,右侧UCLP的牙弓关系结果更差,然而,这些差异未达到统计学显著性。需要使用更大样本量进行进一步研究,以确定在研究UCLP牙弓结果时,腭裂侧别是否是一个重要的考虑因素。