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新西兰单侧唇腭裂患儿的腭裂侧别与牙弓关系结局

Cleft Laterality Dental Arch Relationship Outcomes for Children with Unilateral Cleft Lip and Palate in New Zealand.

作者信息

Fowler Peter V, Keall H, Kennedy D, Healey D, Thompson J M D

机构信息

Department of Oral Sciences, University of Otago Dental School, Dunedin, New Zealand.

Formerly Hospital Dental Department, Middlemore Hospital, Auckland, New Zealand.

出版信息

Cleft Palate Craniofac J. 2025 Jun;62(6):959-963. doi: 10.1177/10556656241234599. Epub 2024 Feb 27.

Abstract

ObjectivesTo investigate cleft laterality dental arch relationship outcomes of children with non-syndromic complete unilateral cleft lip and palate (UCLP) in New Zealand.DesignA retrospective nationwide study.SettingsVirtual 3D orthodontic study models collected prior to undertaking secondary alveolar bone grafting.ParticipantsA total of 104 patients with UCLP (L = 80: R = 24).Outcome measuresFour calibrated assessors used the GOSLON Yardstick and 100 mm Visual Analogue Scale (VAS) to score the randomised models on 2 separate assessment sessions. Weighted Kappa were used to determine the intra/inter-rater reliability for the GOSLON and correlations for the VAS.ResultsIntra-rater reliability ranged from 0.57-0.88 (GOSLON) and 0.45-0.93 (VAS). Inter-rater reliability ranged from 0.62-0.86 (GOSLON) and 0.64-0.93 (VAS).GOSLON scores for the left UCLP were 31.2% for good/very good; 26.3% for fair; 42.5% for poor/very poor while the right UCLP scored 8.3% for good/very good; 37.5% for fair; 54.2% for poor/very poor. The mean VAS for left and right UCLP were 53.4 (sd 22.5) and 44.6 (sd 17.1) respectively. Neither the GOSLON nor VAS differences reached statistical significance (both  = .08).ConclusionsFrom a clinical perspective right UCLP had worse dental arch relationship outcomes, however, these differences failed to reach statistical significance. Further studies using larger sample sizes are required to determine if cleft laterality is an important consideration when investigating UCLP dental arch outcomes.

摘要

目的

调查新西兰非综合征性完全性单侧唇腭裂(UCLP)患儿的腭裂侧别与牙弓关系结果。

设计

一项全国性回顾性研究。

设置

在进行二次牙槽骨植骨术前收集的虚拟3D正畸研究模型。

参与者

共有104例UCLP患者(左侧=80例;右侧=24例)。

观察指标

4名经过校准的评估者使用戈斯隆标尺和100毫米视觉模拟量表(VAS)在2个独立的评估环节对随机模型进行评分。加权kappa系数用于确定戈斯隆评分的评分者内/评分者间信度以及VAS评分的相关性。

结果

评分者内信度范围为0.57 - 0.88(戈斯隆)和0.45 - 0.93(VAS)。评分者间信度范围为0.62 - 0.86(戈斯隆)和0.64 - 0.93(VAS)。

左侧UCLP的戈斯隆评分为:良好/非常好占31.2%;中等占26.3%;差/非常差占42.5%,而右侧UCLP评分为:良好/非常好占8.3%;中等占37.5%;差/非常差占54.2%。左侧和右侧UCLP的VAS平均评分分别为53.4(标准差22.5)和44.6(标准差17.1)。戈斯隆评分和VAS评分的差异均未达到统计学显著性(均P = 0.08)。

结论

从临床角度看,右侧UCLP的牙弓关系结果更差,然而,这些差异未达到统计学显著性。需要使用更大样本量进行进一步研究,以确定在研究UCLP牙弓结果时,腭裂侧别是否是一个重要的考虑因素。

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本文引用的文献

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Cleft Palate Craniofac J. 2022 Jul;59(7):899-909. doi: 10.1177/10556656211028506. Epub 2021 Jul 8.

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