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肾移植患者播散性鼻疽诺卡菌感染:一例报告

Disseminated Nocardia farcinica Infection in a Renal Transplant Patient: A Case Report.

作者信息

Mustafa Alhashimi Fatma, Salim Sara, Iqbal Asif, Balila Maida, Chishti Muhammed Khalid

机构信息

College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, ARE.

Department of Infectious Disease, Mediclinic City Hospital, Dubai, ARE.

出版信息

Cureus. 2024 Feb 26;16(2):e54963. doi: 10.7759/cureus.54963. eCollection 2024 Feb.

DOI:10.7759/cureus.54963
PMID:38414516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10897754/
Abstract

, an aerobic, Gram-positive bacterium belonging to the genus , is a challenging opportunistic pathogen, particularly impacting immunocompromised individuals. The prevalence of human disease has witnessed a notable rise over the past two decades, correlating with an expanding population of immunocompromised individuals and advancements in the detection and identification of spp. within clinical laboratories. This case is of a 59-year-old male with compromised immunity due to immunosuppressive medication use following a renal transplant who had an array of presentations before confirming a diagnosis of disseminated nocardiosis. The challenges faced in our case provide valuable insights into the complexities associated with diagnosing and managing infections in immunocompromised populations, informing future clinical practice and research endeavors.

摘要

[细菌名称]是一种需氧的革兰氏阳性菌,属于[菌属名称],是一种具有挑战性的机会致病菌,尤其会影响免疫功能低下的个体。在过去二十年中,人类疾病的患病率显著上升,这与免疫功能低下个体数量的增加以及临床实验室中[细菌名称]属细菌检测和鉴定技术的进步相关。本病例为一名59岁男性,因肾移植后使用免疫抑制药物导致免疫力受损,在确诊播散性诺卡菌病之前有一系列症状表现。我们病例中所面临的挑战为免疫功能低下人群中诺卡菌感染的诊断和管理相关复杂性提供了宝贵见解,为未来的临床实践和研究工作提供了参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcdb/10897754/4066754c3d52/cureus-0016-00000054963-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcdb/10897754/91160eeb0840/cureus-0016-00000054963-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcdb/10897754/4066754c3d52/cureus-0016-00000054963-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcdb/10897754/91160eeb0840/cureus-0016-00000054963-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcdb/10897754/4066754c3d52/cureus-0016-00000054963-i02.jpg

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Braz J Infect Dis. 2023 Sep-Oct;27(5):102806. doi: 10.1016/j.bjid.2023.102806. Epub 2023 Oct 3.
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Mortality After Nocardiosis: Risk Factors and Evaluation of Disseminated Infection.诺卡菌病后的死亡率:危险因素及播散性感染评估
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Brain Abscess Caused by Nocardia farcinica in a Young Immunocompetent Patient.一名年轻免疫功能正常患者发生的鼻疽诺卡菌引起的脑脓肿
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