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联合抗病毒治疗作为严重急性呼吸综合征冠状病毒2感染期间异基因造血干细胞移植的有效可行选择:一例病例报告

Combined antiviral therapy as effective and feasible option in allogenic hematopoietic stem cell transplantation during SARS-COV-2 infection: a case report.

作者信息

Vita Serena, D'Abramo Alessandra, Coppola Andrea, Farroni Chiara, Iori Anna Paola, Faraglia Francesca, Sette Alessandro, Grifoni Alba, Lindestam Arlehamn Cecilia, Bibas Michele, Goletti Delia, Nicastri Emanuele

机构信息

Clinical Department, National Institute for Infectious Diseases 'Lazzaro Spallanzani' Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.

Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.

出版信息

Front Oncol. 2024 Feb 13;14:1290614. doi: 10.3389/fonc.2024.1290614. eCollection 2024.

Abstract

Here we describe the case of a 51 years old Italian woman with acute lymphoblastic leukemia who underwent to hematopoietic stem cell transplantation (HSCT) during SARS-COV-2 infection. She presented a prolonged COVID-19 successfully treated with dual anti SARS-COV-2 antiviral plus monoclonal antibody therapy.

摘要

在此,我们描述了一名51岁的意大利女性急性淋巴细胞白血病患者的病例,她在感染SARS-CoV-2期间接受了造血干细胞移植(HSCT)。她出现了长时间的COVID-19,通过双重抗SARS-CoV-2抗病毒药物加单克隆抗体治疗成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1345/10896944/b5c6c97894c2/fonc-14-1290614-g001.jpg

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