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加拿大安大略省姑息治疗医生的姑息镇静实践与观点:一项混合方法研究

Practices of and Perspectives on Palliative Sedation Among Palliative Care Physicians in Ontario, Canada: A Mixed-Methods Study.

作者信息

Nolen Amy, Selby Debbie, Qureshi Fahad, Mills Anneliese

机构信息

Department of Family and Community Medicine and University of Toronto, Toronto, Ontario, Canada.

Division of Palliative Care and Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

出版信息

Palliat Med Rep. 2024 Feb 13;5(1):94-103. doi: 10.1089/pmr.2023.0081. eCollection 2024.

DOI:10.1089/pmr.2023.0081
PMID:38415075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10898238/
Abstract

BACKGROUND

Palliative sedation (PS) is a therapeutic intervention employed to manage severe and refractory symptoms in terminally ill patients at end of life. Inconsistencies in PS practice guidelines coupled with clinician ambiguity have resulted in confusion about how PS is best integrated into practice. Understanding the perspectives, experiences, and practices relating to this modality will provide insight into its clinical application and challenges within the palliative care landscape.

OBJECTIVE

The aim is to explore the perspectives of palliative care physicians administering PS, including how practitioners define PS, factors influencing decision making about the use of PS, and possible reasons for changes in practice patterns over time.

METHODS

A survey ( = 37) and semistructured interviews ( = 23) were conducted with palliative care physicians throughout Ontario. Codes were determined collaboratively and applied line-by-line by two independent investigators. Survey responses were analyzed alongside interview transcripts and noted to be concordant. Themes were generated through reflexive thematic analysis.

RESULTS

Five key themes were identified: (1) lack of standardization, (2) differing definitions, (3) logistical challenges, (4) perceived "back-up" to Medical Assistance in Dying, and (5) tool of the most responsible physician.

CONCLUSION

There was significant variability in how participants defined PS and in frequency of use of PS. Physicians described greater ease implementing PS when practicing in palliative care units, with significant barriers faced by individuals providing home-based palliative care or working as consultants on inpatient units. Educational efforts are required about the intent and practice of PS, particularly among inpatient interprofessional teams.

摘要

背景

姑息性镇静(PS)是一种用于管理临终患者严重且难治性症状的治疗干预措施。PS实践指南的不一致以及临床医生的含糊不清导致了关于如何将PS最佳地融入实践的困惑。了解与这种方式相关的观点、经验和实践将有助于洞察其在姑息治疗领域的临床应用和挑战。

目的

旨在探讨实施PS的姑息治疗医生的观点,包括从业者如何定义PS、影响PS使用决策的因素以及随着时间推移实践模式变化的可能原因。

方法

对安大略省各地的姑息治疗医生进行了一项调查(n = 37)和半结构化访谈(n = 23)。代码由两名独立研究人员共同确定并逐行应用。调查回复与访谈记录一起进行分析,并注意到两者一致。通过反思性主题分析生成主题。

结果

确定了五个关键主题:(1)缺乏标准化,(2)定义不同,(3)后勤挑战,(4)被视为对临终医疗协助的“后备”,以及(5)最负责医生的工具。

结论

参与者对PS的定义以及PS的使用频率存在显著差异。医生们表示,在姑息治疗病房工作时实施PS更容易,而提供居家姑息治疗的个人或在住院病房担任顾问的人员面临重大障碍。需要开展关于PS意图和实践的教育工作,特别是在住院跨专业团队中。

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Clinical Practice Guideline for Care in the Last Days of Life.生命终末期护理临床实践指南
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Use of palliative sedation following Medical Assistance in Dying (MAiD) legislation: A mixed-methods study of palliative care providers.使用医疗协助自杀(MAiD)立法后的姑息性镇静治疗:姑息治疗提供者的混合方法研究。
Palliat Support Care. 2023 Aug;21(4):570-577. doi: 10.1017/S1478951523000706.
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Cross-cultural comparison of continuous deep sedation for advanced cancer patients in East Asian countries: prospective cohort study.东亚国家晚期癌症患者持续深度镇静的跨文化比较:前瞻性队列研究。
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Review of European Guidelines on Palliative Sedation: A Foundation for the Updating of the European Association for Palliative Care Framework.欧洲缓和医疗镇静指南回顾:为更新欧洲姑息治疗协会框架奠定基础。
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Impact of legalization of Medical Assistance in Dying on the Use of Palliative Sedation in a Tertiary Care Hospital: A Retrospective Chart Review.《在一家三级护理医院中,协助死亡合法化对姑息性镇静使用的影响:一项回顾性图表审查》。
Am J Hosp Palliat Care. 2022 Apr;39(4):442-447. doi: 10.1177/10499091211030443. Epub 2021 Jul 6.
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Clinical Patterns of Continuous and Intermittent Palliative Sedation in Patients With Terminal Cancer: A Descriptive, Observational Study.终末期癌症患者持续和间断性姑息性镇静的临床模式:一项描述性、观察性研究。
J Pain Symptom Manage. 2019 Jul;58(1):65-71. doi: 10.1016/j.jpainsymman.2019.04.019. Epub 2019 Apr 23.
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Description of Continuous Palliative Sedation Practices in a Large Health Region and Comparison with Clinical Practice Guidelines.描述一个大型卫生区域内持续姑息性镇静实践,并与临床实践指南进行比较。
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Reflections on palliative sedation.关于姑息性镇静的思考
Palliat Care. 2019 Jan 27;12:1178224218823511. doi: 10.1177/1178224218823511. eCollection 2019.
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Changes in opinions on palliative sedation of palliative care specialists over 16 years and their effects on clinical practice.16 年来姑息治疗专家对姑息镇静治疗观念的变化及其对临床实践的影响。
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