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Chemotherapy combined with targeted therapy and immunotherapy is an option in advanced biliary tract cancer.

作者信息

Ge Penglei, Wu Yang

机构信息

Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, Henan 450052, China.

Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

出版信息

Therap Adv Gastroenterol. 2024 Feb 26;17:17562848241234509. doi: 10.1177/17562848241234509. eCollection 2024.

DOI:10.1177/17562848241234509
PMID:38415196
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10898297/
Abstract
摘要

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Efficacy and safety of a triple combination of atezolizumab, bevacizumab plus GEMOX for advanced biliary tract cancer: a multicenter, single-arm, retrospective study.阿替利珠单抗、贝伐单抗联合GEMOX三联疗法治疗晚期胆管癌的疗效和安全性：一项多中心、单臂、回顾性研究
Therap Adv Gastroenterol. 2023 Mar 28;16:17562848231160630. doi: 10.1177/17562848231160630. eCollection 2023.
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Validation study of postoperative liver failure and mortality risk scores after liver resection for perihilar cholangiocarcinoma.肝门部胆管癌肝切除术后肝功能衰竭及死亡风险评分的验证研究
Hepatobiliary Surg Nutr. 2022 Jun;11(3):375-385. doi: 10.21037/hbsn-20-660.
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Novel biomarkers and the future of targeted therapies in cholangiocarcinoma: a narrative review.胆管癌中的新型生物标志物与靶向治疗的未来：一篇叙述性综述
Hepatobiliary Surg Nutr. 2022 Apr;11(2):253-266. doi: 10.21037/hbsn-20-475.
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Conversion therapy of stage IVb unresectable gallbladder carcinoma.IVb期不可切除胆囊癌的转化治疗
Hepatobiliary Surg Nutr. 2022 Apr;11(2):335-337. doi: 10.21037/hbsn-22-78.
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Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study.ivosidenib 治疗 IDH1 突变、化疗耐药性胆管癌（ClarIDHy）：一项多中心、随机、双盲、安慰剂对照、3 期研究。
Lancet Oncol. 2020 Jun;21(6):796-807. doi: 10.1016/S1470-2045(20)30157-1. Epub 2020 May 13.
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Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study.培米替尼治疗既往治疗过的局部晚期或转移性胆管癌：一项多中心、开放标签、2 期研究。
Lancet Oncol. 2020 May;21(5):671-684. doi: 10.1016/S1470-2045(20)30109-1. Epub 2020 Mar 20.
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Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study.帕博利珠单抗治疗非结直肠癌高度微卫星不稳定/错配修复缺陷型癌症患者的疗效：来自 II 期 KEYNOTE-158 研究的结果。
J Clin Oncol. 2020 Jan 1;38(1):1-10. doi: 10.1200/JCO.19.02105. Epub 2019 Nov 4.
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Science. 2018 Mar 23;359(6382):1350-1355. doi: 10.1126/science.aar4060. Epub 2018 Mar 22.
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