柔红霉素酮的(7S)-O-环氧烷基衍生物的合成及生物活性
Synthesis and biological activity of (7S)-O-epoxyalkyl derivatives of daunomycinone.
作者信息
Prikrylová V, Lipavská H, Jizba J V, Fuska J, Podojil M, Vanĕk Z
出版信息
J Antibiot (Tokyo). 1985 Dec;38(12):1714-8. doi: 10.7164/antibiotics.38.1714.
PMID:3841537
Abstract
Synthesis and antibacterial activity of a number of 7-O-epoxyalkyl derivatives of daunomycinone prepared from 7-O-alkenyl derivatives of daunomycinone are described along with their inhibitory effect on leukemia P 388 cells.
摘要
本文描述了由柔红霉素酮的7-O-烯基衍生物制备的多种柔红霉素酮的7-O-环氧烷基衍生物的合成及其抗菌活性，以及它们对白血病P 388细胞的抑制作用。
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