妊娠合并丙型肝炎患者的母婴结局 - 2018-2021 年美国三个州。
Birth Outcomes Among People with Hepatitis C in Pregnancy - Three U.S. States, 2018-2021.
机构信息
Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Eagle Global Scientific, LLC, San Antonio, TX, USA.
出版信息
Matern Child Health J. 2024 Jun;28(6):979-983. doi: 10.1007/s10995-024-03917-3. Epub 2024 Feb 28.
INTRODUCTION
There are limited and conflicting data regarding the impact of hepatitis C in pregnancy on adverse birth outcomes.
METHODS
Using the Surveillance for Emerging Threats to Pregnant People and Infants Network (SET-NET), a large surveillance cohort, we describe birth outcomes among a cohort of people with HCV in pregnancy in total and by reported substance use.
RESULTS
Among 1418 infants, 89% were born to people with reported substance use during pregnancy. The proportion born preterm was 20%, 13% were small-for-gestational age and 34% of term infants required intensive care.
CONCLUSIONS
Assessments of recent changes to recommendations for HCV screening in pregnancy should evaluate the impact on maternal access to care for both HCV treatment as well as comorbidities such as substance use disorder which may contribute to adverse birth outcomes.
简介
关于丙型肝炎对妊娠不良出生结局的影响，目前的数据有限且存在冲突。
方法
利用监测孕妇和婴儿新兴威胁网络（SET-NET）这一大规模监测队列，我们描述了丙型肝炎孕妇队列的出生结局，以及按报告的物质使用情况进行的分类。
结果
在 1418 名婴儿中，89%的婴儿的母亲在怀孕期间有物质使用报告。早产儿的比例为 20%，13%的婴儿为小于胎龄儿，34%的足月婴儿需要重症监护。
结论
评估近期丙型肝炎病毒筛查建议的变化，应该评估其对母亲获得丙型肝炎病毒治疗以及物质使用障碍等合并症的医疗服务的影响，这些合并症可能会导致不良的出生结局。
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