Department of Kinesiology and Physical Education, Wilfrid Laurier University, Waterloo, Ontario, Canada.
Appetite. 2024 May 1;196:107286. doi: 10.1016/j.appet.2024.107286. Epub 2024 Feb 26.
Research on exercise-induced appetite suppression often does not include resistance training (RT) exercise and only compared matched volumes.
To compare the effects of low-load and high-load RT exercise completed to volitional fatigue on appetite-regulation.
11 resistance-trained males (24 ± 2 y) completed 3 sessions in a crossover experimental design: 1) control (CTRL); 2) RT exercise at 30% 1-repetition maximum (RM); and 3) RT exercise at 90% 1-RM. RT sessions consisted of 3 sets of 5 exercises completed to volitional fatigue. Acylated ghrelin, active glucagon-like peptide-1 (GLP-1), active peptide tyrosine (PYY), lactate, and subjective appetite perceptions were measured pre-exercise, 0-, 60-, and 120-min post-exercise. Energy intake was recorded the day before, of, and after each session.
Lactate was elevated following both 30% (0-, 60-, 120-min post-exercise) and 90% (0-, 60-min post-exercise; P < 0.001, d > 3.92) versus CTRL, with 30% greater than 90% (0-min post-exercise; P = 0.011, d = 1.14). Acylated ghrelin was suppressed by 30% (P < 0.007, d > 1.22) and 90% (P < 0.028, d > 0.096) post-exercise versus CTRL, and 30% suppressed concentrations versus 90% (60-min post-exercise; P = 0.032, d = 0.95). There was no effect on PYY (P > 0.171, η <0.149) though GLP-1 was greater at 60-min post-exercise in 90% (P = 0.052, d = 0.86) versus CTRL. Overall appetite was suppressed 0-min post-exercise following 30% and 90% versus CTRL (P < 0.013, d > 1.10) with no other differences (P > 0.279, d < 0.56). There were no differences in energy intake (P > 0.101, η <0.319).
RT at low- and high-loads to volitional fatigue induced appetite suppression coinciding with changes in acylated ghrelin though limited effects on anorexigenic hormones or free-living energy intake were present.
目的：比较低负荷和高负荷的抗阻训练（RT）运动至力竭对食欲调节的影响。
方法：11 名有经验的男性（24 ± 2 岁）完成了 3 次交叉实验设计的试验：1）对照（CTRL）；2）30% 1 重复最大（RM）的 RT 运动；3）90% 1-RM 的 RT 运动。RT 训练包括 3 组 5 个练习，直至达到自愿疲劳。在运动前、0 分钟、60 分钟和 120 分钟时测量酰化 ghrelin、活性胰高血糖素样肽-1（GLP-1）、活性肽酪氨酸（PYY）、乳酸和主观食欲感知。在每次训练前、训练中和训练后记录能量摄入。
结果：与对照相比，30%（0 分钟、60 分钟和 120 分钟 post-exercise）和 90%（0 分钟和 60 分钟 post-exercise；P < 0.001，d > 3.92）时乳酸升高，30%时比 90%时更高（0 分钟 post-exercise；P = 0.011，d = 1.14）。与对照相比，酰化 ghrelin 在 30%（P < 0.007，d > 1.22）和 90%（P < 0.028，d > 0.096）运动后受到抑制，而 30%运动后的浓度比 90%运动后更高（60 分钟 post-exercise；P = 0.032，d = 0.95）。尽管在 90%时 GLP-1 在 60 分钟时更高（P = 0.052，d = 0.86），但 PYY 没有影响（P > 0.171，η <0.149）。与对照相比，30%和 90%在 0 分钟 post-exercise 时总体食欲受到抑制（P < 0.013，d > 1.10），但没有其他差异（P > 0.279，d < 0.56）。能量摄入无差异（P > 0.101，η <0.319）。
结论：低负荷和高负荷的 RT 运动至自愿疲劳都会引起食欲抑制，同时酰化 ghrelin 也会发生变化，尽管对厌食激素或自由生活能量摄入的影响有限。
